Kenzari M
Arch Inst Pasteur Tunis. 1979 Mar-Jun;56(1-2):39-52.
Several "in vitro" methods are developed to study cellular immunity as same as study of antibodies in humoral immunity exploration. The more used in human pathologics are the enumeration of thymus-derived (T) lymphocytes by the formation of nonimmune rosettes E with sheep erythocytes and bone marrow (B) lymphocytes by the presence of membrane-bound immunglobulins; the detection of lymphocyte activation by measuring proliferation (lymphocyte transformation); the mixed lymphocyte reaction, the elaboration of biologically active mediators (lymphokines) and the lymphocyte-mediated cytoxicity.
人们开发了几种“体外”方法来研究细胞免疫,就如同在体液免疫研究中研究抗体一样。在人类病理学中应用较多的方法有:通过与绵羊红细胞形成非免疫性E花环来计数胸腺来源的(T)淋巴细胞,以及通过检测膜结合免疫球蛋白来计数骨髓(B)淋巴细胞;通过测量增殖(淋巴细胞转化)来检测淋巴细胞激活;混合淋巴细胞反应、生物活性介质(淋巴因子)的产生以及淋巴细胞介导的细胞毒性。