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淀粉性皮炎:豚鼠体内手术手套粉末免疫原性的证据。

Starch dermatitis: evidence of immunogenicity of surgical glove powder in the guinea-pig.

作者信息

Grant J B, Davies J D, Verrier Jones J

出版信息

Br J Exp Pathol. 1975 Oct;56(5):396-401.

Abstract

Guinea-pigs immunized by nuchal inoculation of starch glove powder emulsified with Freund's complete adjuvant showed increased thickening of the ear erythema and monoculear inflammation after local injection of 0.1 mg starch compared with similarly treated control animals inoculated with saline and Freund's complete adjuvant. The responses in the ear of the immunized animals were most pronounceed 3-4 weeks after immunization and 24-72 h after local challenge. It is suggested that the inflammatory response in the immunized guinea-pig has 2 components: reaction to a primary irritant in the glove powder and delayed hypersensitivity to an unidentified component of the glove powder.

摘要

通过颈部接种用弗氏完全佐剂乳化的淀粉手套粉免疫的豚鼠,与接种生理盐水和弗氏完全佐剂的同样处理的对照动物相比,在局部注射0.1毫克淀粉后,耳部红斑增厚和单核细胞炎症增加。免疫动物耳部的反应在免疫后3 - 4周以及局部激发后24 - 72小时最为明显。提示免疫的豚鼠中的炎症反应有两个成分:对手套粉中主要刺激物的反应和对未鉴定的手套粉成分的迟发型超敏反应。

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Allergic starch peritonitis in the guinea-pig.豚鼠过敏性淀粉样腹膜炎。
Br J Surg. 1976 Nov;63(11):867-9. doi: 10.1002/bjs.1800631108.

引用本文的文献

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Hazards of surgical glove powders.手术手套粉末的危害。
Br Med J. 1980 Nov 29;281(6253):1493-4. doi: 10.1136/bmj.281.6253.1493-c.
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Starch synovitis.淀粉性滑膜炎
J Clin Pathol. 1984 Sep;37(9):990-2. doi: 10.1136/jcp.37.9.990.

本文引用的文献

1
GRANULOMATOUS PERITONITIS SECONDARY TO CORN STARCH.继发于玉米淀粉的肉芽肿性腹膜炎
Ann Intern Med. 1965 Feb;62:335-47. doi: 10.7326/0003-4819-62-2-335.
6
Histology of allergic inflammation.变应性炎症的组织学
Br Med Bull. 1967 Jan;23(1):35-8. doi: 10.1093/oxfordjournals.bmb.a070513.
8
Starch granulomatosis of the peritoneum.腹膜淀粉样变性
Br Med J. 1971 Sep 11;3(5775):625-9. doi: 10.1136/bmj.3.5775.625.
9
The histopathology of peritoneal starch granulomas.腹膜淀粉样肉芽肿的组织病理学
J Pathol. 1972 Aug;107(4):265-78. doi: 10.1002/path.1711070406.
10
Delayed hypersensitivity and polysaccharide-containing antigens.迟发型超敏反应与含多糖抗原
Br Med Bull. 1967 Jan;23(1):72-5. doi: 10.1093/oxfordjournals.bmb.a070520.

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