Wang Qinan, Furlong William, Feeny David, Torrance George, Barr Ronald
Division of Economics and Statistics, School of Accountancy and Business, Nanyang Technological University, Singapore.
Med Decis Making. 2002 Jul-Aug;22(4):350-8. doi: 10.1177/0272989X0202200413.
The utility function for the Health Utilities Index Mark 2 (HUI2) system is based on preference measurements from a random sample of parents with exclusion of inconsistent respondents. Would results without exclusions or from a different group of parents have differed?
Scores were obtained from parents of patients (n = 59) undergoing treatment for cancer. Mean scores from the 2 sets of parents were compared:parents of patients and parents from the general population. Three multiattribute utility functions were estimated. Mean scores for HUI2 states using the functions were compared.
Most differences in mean scores between different groups were not statistically significant (P < 0.05). Differences in parameter estimates among the 3 utility functions were 0.05 or less. The exponent on the power function for the parent-of-patient group was 2.16, within 6% of that for random sample parents. The intraclass correlation between scores for 144 health states derived from the random-sample-parents and parents-of-patients functions was 0.99; the mean difference per state in scores was 0.018.
The HUI2 scoring function generalizes well in that different groups of parents give similar results. The HUI2 scoring function is robust in that the functions without and with exclusions generate scores that are very close in value.
健康效用指数第二代（HUI2）系统的效用函数基于对随机抽样父母的偏好测量，排除了回答不一致的受访者。若不进行排除或采用不同组别的父母，结果会有所不同吗？
从正在接受癌症治疗的患者的父母（n = 59）那里获取分数。比较了两组父母的平均分数：患者的父母和一般人群的父母。估计了三个多属性效用函数。比较了使用这些函数得出的HUI2状态的平均分数。
不同组之间平均分数的大多数差异无统计学意义（P < 0.05）。三个效用函数之间的参数估计差异为0.05或更小。患者父母组幂函数的指数为2.16，与随机抽样父母组的指数相差在6%以内。从随机抽样父母和患者父母函数得出的144种健康状态分数之间的组内相关性为0.99；每种状态分数的平均差异为0.018。
HUI2评分函数具有良好的通用性，因为不同组别的父母给出了相似的结果。HUI2评分函数具有稳健性，因为有无排除的函数生成的分数在数值上非常接近。
