Walsh R M, Ponsky J L, Dumot J
Department of General Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Surg Endosc. 2002 Jun;16(6):981-4. doi: 10.1007/s00464-001-8236-1. Epub 2002 Mar 5.
Pain following cholecystectomy can pose a diagnostic and therapeutic dilemma. We reviewed our experience with calculi retained in gallbladder and cystic duct remnants that present with recurrent biliary symptoms.
Over the last 6 years, seven patients were referred to us for the evaluation of recurrent biliary colic or jaundice. There were four men and three women ranging in age from 35 to 70 years. All seven had biliary pain similar to the symptoms that precede cholecystectomy; two of them also had also associated jaundice and one had pancreatitis. The time from cholecystectomy to onset of symptoms ranged from 14 months to 20 years (median, 8.5 Years). Four had undergone laparoscopic cholecystectomy and three had had an open cholecystectomy; none had an operative cholangiogram.
Five of seven underwent diagnostic endoscopic retrograde cholangiography (ERC), which revealed obvious filling defects in the cystic duct or gallbladder remnant. The final patient was diagnosed by laparoscopic ultrasound after eight negative radiographic studies. Four patients underwent laparotomy and resection of a retained gallbladder and/or cystic duct. Two patients were treated with extracorporeal shock-wave lithotripsy (ESWL); one of them also required endoscopic biliary holmium laser lithotripsy. One patient underwent successful repeat laparoscopic cholecystectomy. There were no treatment-related complications. At a median follow-up of 11.5 months, all have achieved complete stone clearance and are asymptomatic.
Retained gallbladder and cystic duct calculi can be a source of recurrent biliary pain, and a heightened suspicion may be required to make the diagnosis. This entity can be prevented by accurate identification of the gallbladder-cystic duct junction at cholecystectomy and by routine use of cholangiography. A variety of therapeutic options can be employed to obtain a successful outcome.
胆囊切除术后疼痛可能会带来诊断和治疗上的难题。我们回顾了我们处理胆囊及胆囊管残余结石导致复发性胆道症状的经验。
在过去6年中,7例患者因复发性胆绞痛或黄疸前来我们处评估。其中男性4例,女性3例,年龄在35至70岁之间。所有7例患者均有类似于胆囊切除术前的胆绞痛症状;其中2例还伴有黄疸,1例伴有胰腺炎。从胆囊切除到症状出现的时间为14个月至20年(中位数为8.5年)。4例患者接受了腹腔镜胆囊切除术,3例接受了开腹胆囊切除术;均未进行术中胆管造影。
7例患者中有5例接受了诊断性内镜逆行胆管造影(ERC),显示胆囊管或胆囊残余有明显的充盈缺损。最后1例患者在8次影像学检查阴性后通过腹腔镜超声确诊。4例患者接受了剖腹手术并切除了残留的胆囊和/或胆囊管。2例患者接受了体外冲击波碎石术(ESWL);其中1例还需要内镜下钬激光碎石术。1例患者成功接受了再次腹腔镜胆囊切除术。无治疗相关并发症。中位随访11.5个月时,所有患者结石均完全清除且无症状。
残留的胆囊和胆囊管结石可能是复发性胆绞痛的来源,诊断时可能需要提高警惕。通过在胆囊切除术中准确识别胆囊-胆囊管交界处并常规使用胆管造影可以预防这种情况。可以采用多种治疗方法获得成功的结果。