Rubio Edmundo R, Chang Eduardo E, Kovitz Kevin L
Section of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA.
South Med J. 2002 Aug;95(8):919-21.
Kaposi's sarcoma (KS) is one of the most common causes of pleural effusion in patients with acquired immunodeficiency syndrome (AIDS). Pleural effusions due to KS carry a high morbidity and mortality. Their treatment is difficult, and they respond poorly to chemical pleurodesis. Even systemic chemotherapy against KS has little effect on the pleural effusions. Commonly, repeated therapeutic thoracentesis or chest tube drainage is required. We present a case of advanced KS with bilateral pleural effusions. We believe this is the first reported case in which medical thoracoscopy with talc pleurodesis has been shown to achieve adequate control of the effusions.
卡波西肉瘤(KS)是获得性免疫缺陷综合征(AIDS)患者胸腔积液最常见的病因之一。由KS引起的胸腔积液具有高发病率和死亡率。其治疗困难,对化学性胸膜固定术反应不佳。即使针对KS的全身化疗对胸腔积液也几乎没有效果。通常,需要反复进行治疗性胸腔穿刺或胸腔闭式引流。我们报告一例晚期KS伴双侧胸腔积液的病例。我们认为这是首例报道的通过医用胸腔镜滑石粉胸膜固定术实现对积液充分控制的病例。