Ragasa Consolacion Y, Hofileña Joy G, Rideout John A
Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila, 1004 Philippines.
J Nat Prod. 2002 Aug;65(8):1107-10. doi: 10.1021/np0201523.
Four new cassane-type furanoditerpenoids (1-4) were isolated from the air-dried leaves of Caesalpinia pulcherrima. Their structures were elucidated by spectral data interpretation. The exocyclic methylene compound 1 readily isomerized and oxidized to the benzofuran 4. Benzyl 2,6-dimethoxybenzoate (5) was also identified in this study. Antimicrobial tests on 1-5 indicated that they were active against several bacteria (S. aureus, E. coli, P. aeruginosa, and B. subtilis) and fungi (C. albicans and T. mentagrophytes).
从美丽决明的风干叶中分离出四种新的决明烷型呋喃二萜（1-4）。通过光谱数据解析确定了它们的结构。环外亚甲基化合物1很容易异构化并氧化为苯并呋喃4。本研究中还鉴定出了2,6-二甲氧基苯甲酸苄酯（5）。对1-5进行的抗菌测试表明，它们对几种细菌（金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌和枯草芽孢杆菌）和真菌（白色念珠菌和须癣毛癣菌）具有活性。
