蒂尔西宁A和B：来自一种新的食真菌青霉属物种（NRRL 28147）的新型抗昆虫吲哚二萜类化合物。
Thiersinines A and B: novel antiinsectan indole diterpenoids from a new fungicolous Penicillium species (NRRL 28147).
作者信息
Li Chen, Gloer James B, Wicklow Donald T, Dowd Patrick F
机构信息
Department of Chemistry, University of Iowa, Iowa City 52242, USA.
出版信息
Org Lett. 2002 Sep 5;4(18):3095-8. doi: 10.1021/ol026424a.
[structure: see text] Two novel antiinsectan indole diterpenoids, thiersinines A (1) and B (2), along with seven known paxilline-type compounds, were isolated from organic extracts of a new Penicillium species (P. thiersii NRRL 28147). The structures of 1 and 2 were determined by analysis of 2D NMR data. Thiersinines A and B possess a unique spirocyclic subunit that is unprecedented in previously known compounds of this class. Both compounds exhibit potent activity against the fall armyworm (Spodoptera frugiperda).
[结构：见正文] 从一种新的青霉属物种（蒂尔西青霉NRRL 28147）的有机提取物中分离出两种新型抗昆虫吲哚二萜类化合物，蒂尔西菌素A（1）和B（2），以及七种已知的青霉素型化合物。通过二维核磁共振数据的分析确定了1和2的结构。蒂尔西菌素A和B具有独特的螺环亚基，这在该类先前已知的化合物中是前所未有的。这两种化合物对草地贪夜蛾（Spodoptera frugiperda）均表现出强效活性。
Zotero 插件