Ara Jehan, Sultana Viqar, Qasim Rashida, Ahmad Viqar Uddin
Department of Food Science and Technology, University of Karachi, Karachi-75270, Pakistan.
Phytother Res. 2002 Aug;16(5):479-83. doi: 10.1002/ptr.909.
During the present study, ethanol extracts of five seaweed species Solieria robusta, Iyengaria stellata, Colpomenia sinuosa, Spatoglossum asperum and Caulerpa racemosa at 10 mg/ 200 g body weight were tested for their hypolipidaemic activity. All the species significantly decreased the serum total cholesterol, triglyceride and low density lipoprotein cholesterol levels in normal, triton-induced and diet-induced hyperlipidaemic rats. Solieria robusta was found to be the most effective in reducing the lipid profile, particularly in diet-induced hyperlipidaemic rats. A beneficial effect of the ethanol extract of S. asperum was also found on cardiac and liver enzymes in diet-induced hyperlipidaemic rats.
在本研究中，对五种海藻（强壮索藻、星状伊氏藻、波状网胰藻、粗糙叉节藻和总状蕨藻）的乙醇提取物以10毫克/200克体重的剂量进行了降血脂活性测试。在正常、 Triton诱导和饮食诱导的高脂血症大鼠中，所有这些海藻物种均显著降低了血清总胆固醇、甘油三酯和低密度脂蛋白胆固醇水平。发现强壮索藻在降低血脂方面最有效，尤其是在饮食诱导的高脂血症大鼠中。还发现粗糙叉节藻的乙醇提取物对饮食诱导的高脂血症大鼠的心脏和肝脏酶有有益作用。
