抽搐和嗅吸时经膈压的可重复性。

Reproducibility of twitch and sniff transdiaphragmatic pressures.

作者信息

Luo Y M, Hart N, Mustfa N, Man W D C, Rafferty G F, Polkey M I, Moxham J

机构信息

Department of Respiratory Medicine and Allergy, Respiratory Muscle Laboratory, Guy's, King's and St Thomas' School of Medicine, King's College Hospital, Bessemer Road, London SE5 9PJ, UK.

出版信息

Respir Physiol Neurobiol. 2002 Sep 4;132(3):301-6. doi: 10.1016/s1569-9048(02)00115-5.

DOI:10.1016/s1569-9048(02)00115-5

PMID:12208088

Abstract

Twitch transdiaphragmatic pressure (Tw Pdi) measured with magnetic stimulation of the phrenic nerve is used to follow up patients and to assess the effect of clinical treatments on diaphragm function. However the reproducibility of Tw Pdi on different occasions has been little studied. We investigated 32 normal subjects, measuring Tw Pdi elicited by bilateral magnetic stimulation of the phrenic nerves on two to 14 occasions. Sniff transdiaphragmatic pressure (sniff Pdi) was also measured. The mean value of Tw Pdi and sniff Pdi were 28+/-5 and 134+/-24 cm H(2)O, respectively. The within subjects coefficient of variation was 11% for both Tw Pdi and sniff Pdi. We conclude that there is a variability of Tw Pdi and the variability of Tw Pdi is the same as that of sniff Pdi.

摘要

通过膈神经磁刺激测量的抽搐跨膈压（Tw Pdi）用于随访患者并评估临床治疗对膈肌功能的影响。然而，Tw Pdi在不同时间的可重复性研究较少。我们对32名正常受试者进行了研究，在2至14个不同时间点测量双侧膈神经磁刺激诱发的Tw Pdi。同时也测量了吸气跨膈压（sniff Pdi）。Tw Pdi和sniff Pdi的平均值分别为28±5和134±24 cm H₂O。Tw Pdi和sniff Pdi的受试者内变异系数均为11%。我们得出结论，Tw Pdi存在变异性，且Tw Pdi的变异性与sniff Pdi相同。