关于胸腔积液中的酸性糖胺聚糖（粘多糖）。

On acid glycosaminoglycans (mucopolysaccharides) in pleural effusion.

作者信息

Arai H, Endo M, Yokosawa A, Sato H, Motomiya M

出版信息

Am Rev Respir Dis. 1975 Jan;111(1):37-42. doi: 10.1164/arrd.1975.111.1.37.

DOI:10.1164/arrd.1975.111.1.37

Abstract

The concentration of acid glycosaminoglycans (mucopolysaccharides) in pleural fluid was found to be in the range of 4.0 to 60.3 mug per ml. By chromatographic analysis and by electrophoresis of the eluates, in combination with enzymatic digestion, it was found that pleural fluid contained protein-free hyaluronic acid, protein-bound hyaluronic acid, undersulfated chondroitin sulfate A(C), chondroitin sulfate A(C), protein-bound chondroitin sulfate A(C), and dermatan sulfate. The composition of acid glycosaminoglycans in pleural fluid seems to reflect the metabolism of the pleural cavity.

摘要

发现胸腔积液中酸性糖胺聚糖（粘多糖）的浓度在每毫升4.0至60.3微克的范围内。通过对洗脱液进行色谱分析和电泳，并结合酶消化，发现胸腔积液中含有无蛋白透明质酸、蛋白结合透明质酸、低硫酸化硫酸软骨素A（C）、硫酸软骨素A（C）、蛋白结合硫酸软骨素A（C）和硫酸皮肤素。胸腔积液中酸性糖胺聚糖的组成似乎反映了胸腔的代谢情况。