Singh R S, Hubby J L, Throckmorton L H
Genetics. 1975 Jul;80(3):637-50. doi: 10.1093/genetics/80.3.637.
Heat denaturation studies of three different electrophoretic allozymes of octanol dehydrogenase were performed from 10 species of the Drosophila virilis group. A total of 18 alleles were discovered, and in 3 species in which electrophoretic studies indicated that the locus was monomorphic, heat denaturation showed that the locus was polymorphic. We show that electrophoretic studies underestimate the number of alleles at this locus by a factor of 2.6 in these species. The results are discussed in the light of the continuing controversy over selection and neutral theories of genetic variation.
对果蝇属粗壮果蝇组10个物种的三种不同电泳同工酶辛醇脱氢酶进行了热变性研究。共发现了18个等位基因,在3个物种中,电泳研究表明该位点是单态的,但热变性显示该位点是多态的。我们表明,在这些物种中,电泳研究将该位点的等位基因数量低估了2.6倍。根据关于遗传变异的选择理论和中性理论的持续争议对结果进行了讨论。