Asahina Kinji, Kawada Norifumi, Kristensen Dan Bach, Nakatani Kazuki, Seki Shuichi, Shiokawa Miho, Tateno Chise, Obara Masanobu, Yoshizato Katsutoshi
Tissue Regeneration Project, Hiroshima Prefecture Collaboration of Regional Entities for the Advancement of Technological Excellence, Japan Science and Technology Corporation, Japan.
Biochim Biophys Acta. 2002 Sep 27;1577(3):471-5. doi: 10.1016/s0167-4781(02)00477-3.
This study cloned cDNA of human homologue (hSTAP) of rat stellate cell activation-associated protein (rSTAP). hSTAP gene is on chromosome 17q and is composed of four exons. Various types of cells including hepatic stellate cells expressed hSTAP mRNA. Recombinant hSTAP was a heme protein with the activity of peroxidase. hSTAP can be used as a marker of quiescent stellate cells in human liver.
