感觉运动回路的形成。

The formation of sensorimotor circuits.

作者信息

Goulding Martyn, Lanuza Guillermo, Sapir Tamar, Narayan Sujatha

机构信息

Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Rd, La Jolla, California 92037, USA.

出版信息

Curr Opin Neurobiol. 2002 Oct;12(5):508-15. doi: 10.1016/s0959-4388(02)00371-9.

DOI:10.1016/s0959-4388(02)00371-9

PMID:12367629

Abstract

Recent studies have identified some of the key molecular pathways that control the genesis of spinal sensorimotor circuits. Transcription factors play a central role in these events, regulating both the specification of neurons that constitute these sensorimotor pathways and the expression of downstream molecules that control the wiring up of these neurons into topologically interconnected neuronal networks.

摘要

最近的研究已经确定了一些控制脊髓感觉运动回路形成的关键分子途径。转录因子在这些过程中起着核心作用，既调节构成这些感觉运动途径的神经元的特化，又调节控制这些神经元连接成拓扑互连神经网络的下游分子的表达。