Gerritsen Jorrit
Department of Paediatric Pulmonology, Beatrix Children's Hospital, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Paediatr Respir Rev. 2002 Sep;3(3):184-92. doi: 10.1016/s1526-0542(02)00193-8.
One of the main questions from parents of children with asthma is whether the child will outgrow the disease and what is the role of treatment. All outcome studies show that in the transition period from childhood to adulthood asthma symptoms decrease and thereby asthma seems to be cured. However, the reality is that more than 50% of children with asthma suffer from asthma in adult life. The role of treatment is uncertain, since all studies began in a period when inhaled corticosteroids and other novel medications were not available. The recent findings from a study of bronchial biopsies in subjects in remission from asthma for more than 3 years suggests that asthma might persist throughout life.
哮喘患儿家长的主要问题之一是孩子是否会摆脱这种疾病以及治疗的作用是什么。所有结局研究表明，在从儿童期到成年期的过渡阶段，哮喘症状会减轻，因此哮喘似乎被治愈了。然而，现实情况是，超过50%的哮喘儿童在成年后仍患有哮喘。治疗的作用尚不确定，因为所有研究都是在吸入性糖皮质激素和其他新型药物尚未问世的时期开始的。最近一项对哮喘缓解超过3年的受试者进行支气管活检的研究结果表明，哮喘可能会终生持续存在。
