Wairagkar Niteen, Rota Paul A, Liffick Stephanie, Shaikh Naseem, Padbidri V S, Bellini William J
National Institute of Virology, Pune, India.
J Med Virol. 2002 Dec;68(4):611-4. doi: 10.1002/jmv.10228.
The goal of this study was to conduct the initial genetic characterization wild-type measles viruses currently circulating in India. Reverse transcription-polymerase chain reaction detected measles RNA in 11 of 14 throat swabs collected from sporadic and outbreak-associated cases in the city of Pune, during 1996-1998. Sequence analysis of the H and N genes showed that six sequences were genotype D4, three were genotype D8, and two were genotype A. Continued virologic surveillance in other areas of India as well as neighboring countries will indicate the extent of genetic diversity present among wild-type measles viruses circulating in India.
本研究的目的是对目前在印度流行的野生型麻疹病毒进行初步基因特征分析。1996年至1998年期间，在浦那市从散发病例和与疫情相关的病例中采集的14份咽拭子中，有11份通过逆转录聚合酶链反应检测到麻疹RNA。H和N基因的序列分析表明，六个序列为D4基因型，三个为D8基因型，两个为A基因型。在印度其他地区以及邻国持续进行病毒学监测，将表明在印度流行的野生型麻疹病毒中存在的基因多样性程度。
