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1
The macrolide efflux genetic assembly of Streptococcus pneumoniae is present in erythromycin-resistant Streptococcus salivarius.肺炎链球菌的大环内酯外排基因组合存在于耐红霉素的唾液链球菌中。
Antimicrob Agents Chemother. 2002 Nov;46(11):3690-1. doi: 10.1128/AAC.46.11.3690-3691.2002.
2
Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system.对大环内酯类耐药但对克林霉素敏感的肺炎链球菌和化脓性链球菌：一种由外排系统介导的常见耐药模式。
Antimicrob Agents Chemother. 1996 Aug;40(8):1817-24. doi: 10.1128/AAC.40.8.1817.
3
Macrolide efflux in Streptococcus pneumoniae is mediated by a dual efflux pump (mel and mef) and is erythromycin inducible.肺炎链球菌中的大环内酯外排由双外排泵（mel和mef）介导，且对红霉素具有诱导性。
Antimicrob Agents Chemother. 2005 Oct;49(10):4203-9. doi: 10.1128/AAC.49.10.4203-4209.2005.
4
Composite structure of Streptococcus pneumoniae containing the erythromycin efflux resistance gene mefI and the chloramphenicol resistance gene catQ.含有红霉素外排耐药基因mefI和氯霉素耐药基因catQ的肺炎链球菌复合结构。
Antimicrob Agents Chemother. 2007 Nov;51(11):3983-7. doi: 10.1128/AAC.00790-07. Epub 2007 Aug 20.
5
mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.mefE基因对于肺炎链球菌中耐红霉素的M表型是必需的。
Antimicrob Agents Chemother. 1997 Oct;41(10):2251-5. doi: 10.1128/AAC.41.10.2251.
6
Characterization of a genetic element carrying the macrolide efflux gene mef(A) in Streptococcus pneumoniae.肺炎链球菌中携带大环内酯类外排基因mef(A)的遗传元件的特征分析
Antimicrob Agents Chemother. 2000 Sep;44(9):2585-7. doi: 10.1128/AAC.44.9.2585-2587.2000.
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Tn2009, a Tn916-like element containing mef(E) in Streptococcus pneumoniae.Tn2009，一种肺炎链球菌中含有mef(E)的类Tn916元件。
Antimicrob Agents Chemother. 2004 Jun;48(6):2037-42. doi: 10.1128/AAC.48.6.2037-2042.2004.
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Molecular characterization of macrolide resistance determinants [erm(B) and mef(A)] in Streptococcus pneumoniae and viridans group streptococci (VGS) isolated from adult patients with cystic fibrosis (CF).从成年囊性纤维化（CF）患者中分离出的肺炎链球菌和草绿色链球菌（VGS）中大环内酯类耐药决定因素[erm(B)和mef(A)]的分子特征
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Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae.肺炎链球菌中由外排介导的红霉素抗性转座子的检测
Ann Lab Med. 2015 Jan;35(1):57-61. doi: 10.3343/alm.2015.35.1.57. Epub 2014 Dec 8.
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[Macrolide-resistant Streptococcus pneumoniae in the pediatric population in Beijing].[北京儿童群体中对大环内酯类耐药的肺炎链球菌]
Zhonghua Er Ke Za Zhi. 2004 Dec;42(12):936-9.

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Impact of prophylactic and 'rescue pack' antibiotics on the airway microbiome in chronic lung disease.预防性和“救援包”抗生素对慢性肺病患者气道微生物组的影响。
BMJ Open Respir Res. 2023 Apr;10(1). doi: 10.1136/bmjresp-2022-001335.
2
Case-Control Microbiome Study of Chronic Otitis Media with Effusion in Children Points at Streptococcus salivarius as a Pathobiont-Inhibiting Species.儿童分泌性中耳炎的病例对照微生物组研究表明唾液链球菌是一种抑制病理共生菌的物种。
mSystems. 2021 Apr 20;6(2):e00056-21. doi: 10.1128/mSystems.00056-21.
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Comparative genome analysis reveals key genetic factors associated with probiotic property in Enterococcus faecium strains.比较基因组分析揭示了与屎肠球菌菌株益生菌特性相关的关键遗传因素。
BMC Genomics. 2018 Sep 4;19(1):652. doi: 10.1186/s12864-018-5043-9.
4
Deciphering the distance to antibiotic resistance for the pneumococcus using genome sequencing data.利用基因组测序数据破解肺炎链球菌的抗生素耐药距离。
Sci Rep. 2017 Feb 16;7:42808. doi: 10.1038/srep42808.
5
Emergence of a cell wall protease in the Streptococcus thermophilus population.热链球菌种群中细胞壁蛋白酶的出现。
Appl Environ Microbiol. 2010 Jan;76(2):451-60. doi: 10.1128/AEM.01018-09. Epub 2009 Nov 13.
6
Genetic elements responsible for erythromycin resistance in streptococci.链球菌中负责红霉素抗性的遗传元件。
Antimicrob Agents Chemother. 2009 Feb;53(2):343-53. doi: 10.1128/AAC.00781-08. Epub 2008 Nov 10.
7
Extent of horizontal gene transfer in evolution of Streptococci of the salivarius group.唾液链球菌群链球菌进化过程中水平基因转移的程度。
J Bacteriol. 2007 Feb;189(4):1330-41. doi: 10.1128/JB.01058-06. Epub 2006 Nov 3.
8
Microarray-based detection of 90 antibiotic resistance genes of gram-positive bacteria.基于微阵列的革兰氏阳性菌90种抗生素抗性基因检测
J Clin Microbiol. 2005 May;43(5):2291-302. doi: 10.1128/JCM.43.5.2291-2302.2005.
9
Molecular detection of the macrolide efflux gene: to discriminate or not to discriminate between mef(A) and mef(E).大环内酯类外排基因的分子检测：区分还是不区分mef(A)和mef(E)。
Antimicrob Agents Chemother. 2005 Apr;49(4):1271-8. doi: 10.1128/AAC.49.4.1271-1278.2005.
10
Tn2009, a Tn916-like element containing mef(E) in Streptococcus pneumoniae.Tn2009，一种肺炎链球菌中含有mef(E)的类Tn916元件。
Antimicrob Agents Chemother. 2004 Jun;48(6):2037-42. doi: 10.1128/AAC.48.6.2037-2042.2004.

本文引用的文献

1
Macrolide efflux genes mef(A) and mef(E) are carried by different genetic elements in Streptococcus pneumoniae.大环内酯外排基因mef(A)和mef(E)由肺炎链球菌中的不同遗传元件携带。
J Clin Microbiol. 2002 Mar;40(3):774-8. doi: 10.1128/JCM.40.3.774-778.2002.
2
High proportion of pharyngeal carriers of commensal streptococci resistant to erythromycin in Spanish adults.
J Antimicrob Chemother. 2001 Aug;48(2):225-9. doi: 10.1093/jac/48.2.225.
3
Structure and dissemination of a chromosomal insertion element encoding macrolide efflux in Streptococcus pneumoniae.肺炎链球菌中编码大环内酯外排的染色体插入元件的结构与传播
J Infect Dis. 2001 Jul 1;184(1):56-65. doi: 10.1086/321001. Epub 2001 May 31.
4
Distribution of mef(A) and erm(B) genes in macrolide-resistant blood isolates of viridans group streptococci.
J Antimicrob Chemother. 2001 May;47(5):727-8. doi: 10.1093/jac/47.5.727.
5
Antibiotic resistance rates and macrolide resistance phenotypes of viridans group streptococci from the oropharynx of healthy Greek children.
Int J Antimicrob Agents. 2001 Mar;17(3):195-201. doi: 10.1016/s0924-8579(00)00338-1.
6
Cross-regulation of competence pheromone production and export in the early control of transformation in Streptococcus pneumoniae.肺炎链球菌转化早期调控中感受态信息素产生与输出的交叉调控
Mol Microbiol. 2000 Nov;38(4):867-78. doi: 10.1046/j.1365-2958.2000.02187.x.
7
Characterization of a genetic element carrying the macrolide efflux gene mef(A) in Streptococcus pneumoniae.肺炎链球菌中携带大环内酯类外排基因mef(A)的遗传元件的特征分析
Antimicrob Agents Chemother. 2000 Sep;44(9):2585-7. doi: 10.1128/AAC.44.9.2585-2587.2000.
8
Development of competence in Streptococcus pneumonaie: pheromone autoinduction and control of quorum sensing by the oligopeptide permease.肺炎链球菌能力的发展：信息素自诱导及寡肽通透酶对群体感应的控制
Mol Microbiol. 1998 Jul;29(1):75-83. doi: 10.1046/j.1365-2958.1998.00904.x.
9
Antibiotic resistance mechanisms in bacteria of oral and upper respiratory origin.口腔及上呼吸道来源细菌的抗生素耐药机制
Int J Antimicrob Agents. 1998 Feb;9(4):255-67. doi: 10.1016/s0924-8579(98)00005-3.
10
mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.mefE基因对于肺炎链球菌中耐红霉素的M表型是必需的。
Antimicrob Agents Chemother. 1997 Oct;41(10):2251-5. doi: 10.1128/AAC.41.10.2251.

The macrolide efflux genetic assembly of Streptococcus pneumoniae is present in erythromycin-resistant Streptococcus salivarius.

作者信息

Stadler Christina, Teuber Michael

出版信息

Antimicrob Agents Chemother. 2002 Nov;46(11):3690-1. doi: 10.1128/AAC.46.11.3690-3691.2002.

DOI:10.1128/AAC.46.11.3690-3691.2002
PMID:12384396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC128751/
Abstract
摘要