• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

细胞图像的分形与非分形分析:比较及其在神经元树突分支中的应用

Fractal and nonfractal analysis of cell images: comparison and application to neuronal dendritic arborization.

作者信息

Ristanović D, Nedeljkov V, Stefanović B D, Milosević N T, Grgurević M, Stulić V

机构信息

Department of Biophysics School of Medicine, University of Belgrade, Visegradska 26, 11000 Belgrade, Yugoslavia.

出版信息

Biol Cybern. 2002 Oct;87(4):278-88. doi: 10.1007/s00422-002-0342-1.

DOI:10.1007/s00422-002-0342-1
PMID:12386743
Abstract

Neurons of the rat spinal cord were stained using the Golgi impregnation method. Successfully impregnated neurons from laminae II, III, and VI were subjected to fractal and nonfractal analyses. Fractal analysis was performed using length-related techniques. Since an application of fractal methods to the analysis of dendrite arbor structures requires caution, we adopted as appropriate a nonfractal method proposing a generalized power-law model with two main nonfractal parameters: (i) the anfractuosity, characterizing the degree of dendritic deviation from straight lines; and (ii) an estimate of the total length of arbor dendrites. The anfractuosity can distinguish between two sets of drawings where the fractal methods failed. We also redefine some basic concepts of fractal geometry, present the ruler-counting method, and propose a new definition of fractal dimension.

摘要

采用高尔基浸染法对大鼠脊髓神经元进行染色。对成功浸染的Ⅱ、Ⅲ和Ⅵ层神经元进行分形和非分形分析。分形分析采用与长度相关的技术。由于将分形方法应用于树突分支结构分析时需要谨慎,我们适当地采用了一种非分形方法,该方法提出了一个具有两个主要非分形参数的广义幂律模型:(i)曲折度,表征树突偏离直线的程度;(ii)树突分支总长度的估计值。曲折度能够区分分形方法无法区分的两组图形。我们还重新定义了分形几何的一些基本概念,介绍了标尺计数法,并提出了分形维数的新定义。

相似文献

1
Fractal and nonfractal analysis of cell images: comparison and application to neuronal dendritic arborization.细胞图像的分形与非分形分析:比较及其在神经元树突分支中的应用
Biol Cybern. 2002 Oct;87(4):278-88. doi: 10.1007/s00422-002-0342-1.
2
Fractality of dendritic arborization of spinal cord neurons.脊髓神经元树突分支的分形性。
Neurosci Lett. 2006 Apr 3;396(3):172-6. doi: 10.1016/j.neulet.2005.11.031. Epub 2005 Dec 20.
3
Fractal analysis of the laminar organization of spinal cord neurons.脊髓神经元分层组织的分形分析
J Neurosci Methods. 2005 Aug 15;146(2):198-204. doi: 10.1016/j.jneumeth.2005.02.009. Epub 2005 Mar 17.
4
Application of modified Sholl analysis to neuronal dendritic arborization of the cat spinal cord.改良的Sholl分析在猫脊髓神经元树突分支中的应用。
J Neurosci Methods. 2006 Dec 15;158(2):212-8. doi: 10.1016/j.jneumeth.2006.05.030. Epub 2006 Jun 30.
5
A confirmation of Rexed's laminar hypothesis using the Sholl linear method complemented by nonparametric statistics.使用肖尔线性方法并辅以非参数统计对雷克斯德分层假说的验证。
Neurosci Lett. 2007 Mar 13;414(3):286-90. doi: 10.1016/j.neulet.2006.12.034. Epub 2006 Dec 29.
6
Fractal dimension of apical dendritic arborization differs in the superficial and the deep pyramidal neurons of the rat cerebral neocortex.大鼠大脑新皮质浅层和深层锥体神经元顶端树突分支的分形维数不同。
Neurosci Lett. 2015 Mar 4;589:88-91. doi: 10.1016/j.neulet.2015.01.044. Epub 2015 Jan 17.
7
Fractal analysis of dendrites morphology using modified Richardson's and box counting method.使用改进的理查森法和盒计数法对树突形态进行分形分析。
Theor Biol Forum. 2013;106(1-2):157-68.
8
Early dendrite development in spinal cord cell cultures: a quantitative study.脊髓细胞培养中早期树突发育的定量研究
J Neurosci Res. 1993 Jan;34(1):54-66. doi: 10.1002/jnr.490340107.
9
A single-cell model to study changes in neuronal fractal dimension.一种用于研究神经元分形维数变化的单细胞模型。
Methods. 2001 Aug;24(4):341-5. doi: 10.1006/meth.2001.1204.
10
Modified Richardson's method versus the box-counting method in neuroscience.神经科学中改进的理查森方法与盒计数法的比较
J Neurosci Methods. 2015 Mar 15;242:93-6. doi: 10.1016/j.jneumeth.2015.01.013. Epub 2015 Jan 17.

引用本文的文献

1
The Morphology of Brain Neurons: The Box-Counting Method in the Quantitative Analysis of 2D Images.脑神经元形态学:二维图像定量分析中的方块计数法。
Adv Neurobiol. 2024;36:173-189. doi: 10.1007/978-3-031-47606-8_8.
2
Fractals in Neuroanatomy and Basic Neurosciences: An Overview.神经解剖学和基础神经科学中的分形:概述。
Adv Neurobiol. 2024;36:141-147. doi: 10.1007/978-3-031-47606-8_6.
3
Comparisons of quantitative approaches for assessing microglial morphology reveal inconsistencies, ecological fallacy, and a need for standardization.
定量方法评估小胶质细胞形态的比较研究揭示了不一致性、生态谬误以及标准化的必要性。
Sci Rep. 2022 Oct 28;12(1):18196. doi: 10.1038/s41598-022-23091-2.
4
Polymer Physics-Based Classification of Neurons.基于聚合物物理的神经元分类。
Neuroinformatics. 2023 Jan;21(1):177-193. doi: 10.1007/s12021-022-09605-3. Epub 2022 Oct 3.
5
The Fractal Viewpoint of Tumors and Nanoparticles.肿瘤与纳米粒子的分形观点。
Curr Med Chem. 2023;30(3):356-370. doi: 10.2174/0929867329666220801152347.
6
Epigenetic regulation of osteogenesis: human embryonic palatal mesenchymal cells.骨生成的表观遗传调控:人胚胎腭间充质细胞
Bioinformation. 2011 Jan 6;5(7):278-81. doi: 10.6026/97320630005278.