Dougados Maxime, Hochberg Marc C
Department of Rheumatology B, René Descartes University, Cochin Hospital, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France.
Best Pract Res Clin Rheumatol. 2002 Sep;16(4):495-505.
The concept of spondyloarthropathy was recognized first by clinicians based on the aggregation of several diseases occurring either sequentially in the same patient or simultaneously in a family. This concept was thereafter confirmed by the higher prevalence of the HLA-B27 antigen, not only in the group of patients suffering from an axial involvement of ankylosing spondylitis but also in other diseases belonging to the concept of spondyloarthropathy, i.e. psoriatic arthritis, reactive arthritis, inflammatory-bowel-disease-related arthritis and/or other clinical manifestations such as acute anterior uveitis. Recognition of the concept of the spondyloarthropathy is of great importance not only for research purposes but also in daily practice because such recognition has at least a threefold effect: (a) it permits earlier diagnosis, (b) it facilitates patients' education and monitoring, and (c) it has prognostic implications
脊柱关节病的概念最初是由临床医生认识到的，基于几种疾病在同一患者中相继出现或在一个家族中同时出现的聚集现象。此后，HLA - B27抗原的较高患病率证实了这一概念，不仅在患有强直性脊柱炎轴向受累的患者组中如此，而且在属于脊柱关节病概念的其他疾病中也是如此，即银屑病关节炎、反应性关节炎、炎症性肠病相关关节炎和/或其他临床表现，如急性前葡萄膜炎。认识脊柱关节病的概念不仅对研究目的很重要，而且在日常实践中也很重要，因为这种认识至少有三重作用：(a) 它允许早期诊断，(b) 它便于患者教育和监测，以及(c) 它具有预后意义
