Ventura E C, Gaelzer L R, Zanette J, Marques M R F, Bainy A C D
Depto Bioquímica, CCB, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Mar Environ Res. 2002 Sep-Dec;54(3-5):775-9. doi: 10.1016/s0141-1136(02)00137-x.
The initial sampling in the Marine Monitoring Program (MOMAM), coordinated by the Ministry of Marine Affairs (IEAPM), was performed along the southeast coast of Brazil. Orthopristis ruber samples were collected at Guanabara, Sepetiba and Ilha Grande Bays. Microsomal CYP1A levels and cytosolic cholinesterase (ChE), catalase (CAT) and glutathione S-transferase (GST) activities were measured in the liver of these fish according to established procedures. CAT activity and CYP1A content were significantly higher (P < or = 0.05) in fish caught at Guanabara Bay, which might be due to higher levels of peroxisome proliferators and Ah receptor agonists, respectively, at this site compared to the other sites. Also, lower GST activity was observed in fish from this site, which may possibly be related to the presence of oxidative-stress inducing compounds.
由海洋事务部（IEAPM）协调开展的海洋监测项目（MOMAM）的初始采样工作，是在巴西东南沿海进行的。在瓜纳巴拉湾、塞佩蒂巴湾和大岛湾采集了红锯啮脂鲤样本。按照既定程序，对这些鱼肝脏中的微粒体CYP1A水平以及胞质胆碱酯酶（ChE）、过氧化氢酶（CAT）和谷胱甘肽S-转移酶（GST）活性进行了测定。在瓜纳巴拉湾捕获的鱼中，CAT活性和CYP1A含量显著更高（P≤0.05），这可能分别是由于该地点的过氧化物酶体增殖剂和芳烃受体激动剂水平高于其他地点。此外，在该地点的鱼中观察到较低的GST活性，这可能与氧化应激诱导化合物的存在有关。
