Vanlandingham D L, Davis B S, Lvov D K, Samokhvalov E i, Lvov S D, Black W C, Higgs S, Beaty B J
Department of Pathology, University of Texas Medical Branch, Galveston 77555-0609, USA.
Am J Trop Med Hyg. 2002 Sep;67(3):306-9. doi: 10.4269/ajtmh.2002.67.306.
Nucleotide sequencing was used to characterize unidentified California (CAL) serogroup virus isolates from Russia. These viruses were isolated from mosquitoes and humans during epidemiologic investigations on the role of CAL serogroup viruses in the increased incidence of arboviral encephalitis in Russia. Most of the isolates were identified serologically as snowshoe hare (SSH), Inkoo (INK), and Tahyna (TAH) viruses, but some of the isolates were difficult to classify serologically, suggesting that they could be reassortant viruses. There is evidence that at least 2 of these viruses are not reassortant viruses. Sequence analysis revealed that the Russian viruses differ from other Eurasian and North American CAL serogroup viruses in all of the segments analyzed. They are most closely related to SSH virus. Whether they differ sufficiently to be considered a new group of SSH-like viruses remains to be determined.
采用核苷酸测序对来自俄罗斯的未鉴定的加利福尼亚（CAL）血清群病毒分离株进行特征分析。这些病毒是在关于CAL血清群病毒在俄罗斯虫媒病毒性脑炎发病率增加中所起作用的流行病学调查期间，从蚊子和人类中分离出来的。大多数分离株血清学鉴定为雪兔（SSH）、因库奥（INK）和塔希纳（TAH）病毒，但一些分离株血清学难以分类，提示它们可能是重配病毒。有证据表明这些病毒中至少有2种不是重配病毒。序列分析显示，俄罗斯病毒在所分析的所有片段上均不同于其他欧亚和北美CAL血清群病毒。它们与SSH病毒关系最为密切。它们是否差异足够大到可被视为一类新的SSH样病毒仍有待确定。
