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放线菌素D对金鱼脑RNA合成及被动回避潜伏期的影响(作者译)

[The effects of actinomycin D on the brain RNA synthesis and on the passive avoidance latency in the goldfish (author's transl)].

作者信息

Ohi S

出版信息

Shinrigaku Kenkyu. 1975 Oct;46(4):191-8. doi: 10.4992/jjpsy.46.191.

Abstract

(a) Intracranial injection of actinomycin D (2 mug/10 mul/fish) inhibited about 70% of the goldfish brain RNA synthesis from 3 hours to 4 days later. (b) The goldfish injected actinomycin D intracranially was given the passive avoidance training. Intraday-acquisition (short-term memory) was not blocked but interday-retention (long-term memory) was markedly blocked. It might suggest that the brain RNA synthesis is not related to short-term memory but is necessary for long-term memory.

摘要

(a) 颅内注射放线菌素D(2微克/10微升/鱼)在3小时至4天后抑制了约70%的金鱼脑RNA合成。(b) 对颅内注射放线菌素D的金鱼进行被动回避训练。日内习得(短期记忆)未受阻,但日间保持(长期记忆)明显受阻。这可能表明脑RNA合成与短期记忆无关,但对长期记忆是必要的。

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