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放线菌素D对金鱼脑RNA合成及被动回避潜伏期的影响(作者译)

[The effects of actinomycin D on the brain RNA synthesis and on the passive avoidance latency in the goldfish (author's transl)].

作者信息

Ohi S

出版信息

Shinrigaku Kenkyu. 1975 Oct;46(4):191-8. doi: 10.4992/jjpsy.46.191.

DOI:10.4992/jjpsy.46.191
PMID:1241033
Abstract

(a) Intracranial injection of actinomycin D (2 mug/10 mul/fish) inhibited about 70% of the goldfish brain RNA synthesis from 3 hours to 4 days later. (b) The goldfish injected actinomycin D intracranially was given the passive avoidance training. Intraday-acquisition (short-term memory) was not blocked but interday-retention (long-term memory) was markedly blocked. It might suggest that the brain RNA synthesis is not related to short-term memory but is necessary for long-term memory.

摘要

(a) 颅内注射放线菌素D(2微克/10微升/鱼)在3小时至4天后抑制了约70%的金鱼脑RNA合成。(b) 对颅内注射放线菌素D的金鱼进行被动回避训练。日内习得(短期记忆)未受阻,但日间保持(长期记忆)明显受阻。这可能表明脑RNA合成与短期记忆无关,但对长期记忆是必要的。

相似文献

1
[The effects of actinomycin D on the brain RNA synthesis and on the passive avoidance latency in the goldfish (author's transl)].放线菌素D对金鱼脑RNA合成及被动回避潜伏期的影响(作者译)
Shinrigaku Kenkyu. 1975 Oct;46(4):191-8. doi: 10.4992/jjpsy.46.191.
2
Effects of actinomycin D on brain RNA synthesis and discrimination learning in the goldfish (Carassius auratus).放线菌素D对金鱼(鲫鱼)脑RNA合成及辨别学习的影响。
Physiol Behav. 1977 Aug;19(2):261-4. doi: 10.1016/0031-9384(77)90336-5.
3
Actinomycin D blocks formation of memory of shock-avoidance in goldfish.放线菌素D可阻断金鱼对逃避电击记忆的形成。
Science. 1967 Dec 22;158(3808):1600-1. doi: 10.1126/science.158.3808.1600.
4
Inhibition of long-term memory formation by anti-ependymin antisera after active shock-avoidance learning in goldfish.金鱼主动回避学习后抗室管膜蛋白抗血清对长期记忆形成的抑制作用。
Brain Res. 1988 Feb 23;442(1):53-62. doi: 10.1016/0006-8993(88)91431-x.
5
Effect of intracerebral actinomycin D and of electroconvulsive shock on passive avoidance.
J Comp Physiol Psychol. 1967 Feb;63(1):126-32. doi: 10.1037/h0024147.
6
Short communication: long- but not medium-term retention of olfactory memories in honeybees is impaired by actinomycin D and anisomycin.简短通讯:放线菌素D和茴香霉素会损害蜜蜂嗅觉记忆的长期而非中期保持。
Eur J Neurosci. 1998 Aug;10(8):2742-5. doi: 10.1046/j.1460-9568.1998.00319.x.
7
Role of RNA and protein synthesis in memory formation.RNA与蛋白质合成在记忆形成中的作用。
Neurochem Res. 1979 Jun;4(3):297-312. doi: 10.1007/BF00963800.
8
Camptothecin blocks memory of conditioned avoidance in the goldfish.喜树碱会阻断金鱼对条件性回避的记忆。
Science. 1973 Mar 23;179(4079):1243-6. doi: 10.1126/science.179.4079.1243.
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Cerebral protein synthesis inhibitors block long-term memory.大脑蛋白质合成抑制剂会阻断长期记忆。
Int Rev Neurobiol. 1970;12:177-205. doi: 10.1016/s0074-7742(08)60061-6.
10
Is actinomycin D suitable for the investigation of memory processes?放线菌素D是否适用于记忆过程的研究?
Pharmacol Biochem Behav. 1976 May;4(5):515-9. doi: 10.1016/0091-3057(76)90190-8.

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