Ohi S
Physiol Behav. 1977 Aug;19(2):261-4. doi: 10.1016/0031-9384(77)90336-5.
Intracranial injection of actinomycin D 2 microgram inhibited about 70% of the brain RNA synthesis from 3 hr to 4 days after injection in the goldfish. Under these conditions, fish were given 4-day-training of visual discrimination between a card with vertical stripes and one with horizontal stripes. Fish injected intracranially with actinomycin D showed deficits in between-day retention (long-term memory) but not interruption of within-day acquisition (short-term memory). It is suggested that brain RNA synthesis is necessary only for the formation of long-term memory but not short-term memory.
向金鱼颅内注射2微克放线菌素D，在注射后3小时至4天内，可抑制约70%的脑RNA合成。在这些条件下，对鱼进行为期4天的视觉辨别训练，使其区分带有垂直条纹的卡片和带有水平条纹的卡片。颅内注射放线菌素D的鱼在日间记忆保持（长期记忆）方面存在缺陷，但日间习得（短期记忆）未受影响。这表明脑RNA合成仅对长期记忆的形成是必要的，而对短期记忆则不是。
