Guo Hongwei, Xi Jing
Department of Nutrition and Food Hygiene, School of Public Health, Fudan University, Shanghai 200032, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2002 Jul;36(4):250-3.
To survey the intake of dietary lipids and analyze serum lipid levels in hypertensive patients, and to study the effects of changing dietary lipids intake on the serum lipid levels.
To estimate the intake of dietary fat and to measure the level of serum lipids in hypertensive patients before and after intervention.
The baseline survey showed that the intake of dietary fat and cholesterol were high in those patients. Their fat intake is more than 30% of the total energy intake; serum total cholesterol (TC), triglycerides (TG) and LDL-cholesterol (LDL-C) levels were higher than the normal level. Correlation analysis showed that body mass index (BMI) and saturated fatty acid (SFA) intake were positively correlated with serum TC, TG and LDL-C; serum HDL-C/TC ratio was positively correlated with monounsaturated fatty acid (MUFA) intake, and negatively correlated with BMI and SFA. The results implicated that MUFA is the protective factor against hypertension and hyperlipidemia. After one-year community-based nutrition intervention, the serum TC and LDL-C levels of the intervened subjects were reduced dramatically.
The results indicate that reducing the intake of dietary fat and cholesterol and properly increasing dietary MUFA intake have significant effects on lowering serum lipids levels and controlling blood pressure in hypertensive patients.
调查高血压患者膳食脂质的摄入量并分析其血脂水平，研究改变膳食脂质摄入量对血脂水平的影响。
评估高血压患者干预前后膳食脂肪的摄入量并测量血脂水平。
基线调查显示，这些患者的膳食脂肪和胆固醇摄入量较高。他们的脂肪摄入量超过总能量摄入量的30%；血清总胆固醇（TC）、甘油三酯（TG）和低密度脂蛋白胆固醇（LDL-C）水平高于正常水平。相关性分析表明，体重指数（BMI）和饱和脂肪酸（SFA）摄入量与血清TC、TG和LDL-C呈正相关；血清高密度脂蛋白胆固醇/总胆固醇（HDL-C/TC）比值与单不饱和脂肪酸（MUFA）摄入量呈正相关，与BMI和SFA呈负相关。结果提示，MUFA是预防高血压和高脂血症的保护因素。经过一年的社区营养干预，干预对象的血清TC和LDL-C水平显著降低。
结果表明，减少膳食脂肪和胆固醇的摄入量并适当增加膳食MUFA的摄入量对降低高血压患者的血脂水平和控制血压有显著作用。
