Yamaguchi S, Kaku S, Kuwahara Y, Yamada A
Arch Environ Contam Toxicol. 1975;3(4):488-60. doi: 10.1007/BF02220815.
Epidemiological and experimental studies were carried out in order to evaluate the significance of the amount of organochlorine pesticides in biological specimens. The amount of beta-BHC, DDT and DDE was determined and compared in human plasma samples taken from several different socio-economic groups. The residue pesticides thus determined reflected the difference in the amount of pesticides used for agricultural purposes in respective areas. The highest value of beta-BHC was found among the people of some groups who had taken more fat-rich animal proteins than the people in other groups. It was also noteworthy that the amount of beta-BHC has decreased in the females in the population who have experienced pregnancy more than one time. The animal experiment also showed the effect of pregnancy on the elimination or decomposition of the pesticides in the biological milieu.
为了评估生物样本中有机氯农药含量的意义，开展了流行病学和实验研究。测定并比较了取自几个不同社会经济群体的人体血浆样本中β-六六六、滴滴涕和滴滴伊的含量。如此测定的残留农药反映了各地区农业用途农药使用量的差异。在某些摄入富含脂肪的动物蛋白比其他群体更多的人群中，发现β-六六六含量最高。同样值得注意的是，在多次怀孕的女性人群中，β-六六六含量有所下降。动物实验也显示了怀孕对生物环境中农药消除或分解的影响。
