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Mefloquine: contraindicated in patients with mood, psychotic or seizure disorders.甲氟喹:禁用于患有情绪、精神或癫痫障碍的患者。
CMAJ. 2002 Nov 12;167(10):1147.
2
[Neuropsychiatric side effects of malarial prophylaxis with mefloquine (Lariam)].[使用甲氟喹(疟必清)进行疟疾预防的神经精神副作用]
Harefuah. 1999 Jul;137(1-2):25-7, 87.
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Mefloquine--its 20 years in the Thai Malaria Control Program.甲氟喹——在泰国疟疾控制项目中的20年历程。
Southeast Asian J Trop Med Public Health. 2004 Jun;35(2):300-8.
4
[Convulsions during prophylactic use of mefloquine].[甲氟喹预防性使用期间的惊厥]
Ned Tijdschr Geneeskd. 1999 Jan 30;143(5):273-4.
5
Mefloquine prophylaxis: an overview of spontaneous reports of severe psychiatric reactions and convulsions.甲氟喹预防:严重精神反应和惊厥自发报告概述
J Trop Med Hyg. 1992 Jun;95(3):167-79.
6
Psychosis with paranoid delusions after a therapeutic dose of mefloquine: a case report.服用治疗剂量甲氟喹后出现伴有偏执妄想的精神病:一例报告
Malar J. 2006 Aug 23;5:74. doi: 10.1186/1475-2875-5-74.
7
The efficacy and tolerability of doxycycline and mefloquine in malaria prophylaxis of the ISAF troops in Afghanistan.多西环素和甲氟喹在阿富汗国际安全援助部队疟疾预防中的疗效及耐受性
J Infect. 2005 Oct;51(3):253-8. doi: 10.1016/j.jinf.2005.01.014.
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Mefloquine for malarial prophylaxis in military personnel.甲氟喹用于军事人员的疟疾预防
BMJ. 2015 Nov 3;351:h5797. doi: 10.1136/bmj.h5797.
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Mefloquine-induced mania in a 22-year-old Chinese man.
Singapore Med J. 2006 Jun;47(6):549-50.
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Mefloquine is highly efficacious against chloroquine-resistant Plasmodium vivax malaria and Plasmodium falciparum malaria in Papua, Indonesia.甲氟喹对印度尼西亚巴布亚地区耐氯喹的间日疟原虫疟疾和恶性疟原虫疟疾具有高效。
Clin Infect Dis. 2006 Apr 15;42(8):1067-72. doi: 10.1086/501357. Epub 2006 Mar 13.

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Imported Malaria in Countries where Malaria Is Not Endemic: a Comparison of Semi-immune and Nonimmune Travelers.输入的内容为:Imported Malaria in Countries where Malaria Is Not Endemic: a Comparison of Semi-immune and Nonimmune Travelers. 翻译结果为:非疟疾流行地区输入性疟疾:半免疫旅行者和非免疫旅行者的比较。
Clin Microbiol Rev. 2020 Mar 11;33(2). doi: 10.1128/CMR.00104-19. Print 2020 Mar 18.
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J Parasitol Res. 2015;2015:260106. doi: 10.1155/2015/260106. Epub 2015 Oct 22.
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Idiosyncratic quinoline central nervous system toxicity: Historical insights into the chronic neurological sequelae of mefloquine.奎宁类中枢神经系统毒性的个体差异性:探讨长期使用甲氟喹导致的慢性神经后遗症。
Int J Parasitol Drugs Drug Resist. 2014 Apr 5;4(2):118-25. doi: 10.1016/j.ijpddr.2014.03.002. eCollection 2014 Aug.
4
Mefloquine effects on ventral tegmental area dopamine and GABA neuron inhibition: a physiologic role for connexin-36 GAP junctions.甲氟喹对腹侧被盖区多巴胺和 GABA 神经元抑制的影响:连接蛋白 36 间隙连接的生理作用。
Synapse. 2011 Aug;65(8):804-13. doi: 10.1002/syn.20907. Epub 2011 Apr 7.

本文引用的文献

1
Malaria deaths in visitors to Canada and in Canadian travellers: a case series.加拿大访客及加拿大旅行者中的疟疾死亡病例系列报告
CMAJ. 2001 Mar 6;164(5):654-9.
2
Health advice and immunizations for travelers.旅行者的健康建议与免疫接种
N Engl J Med. 2000 Jun 8;342(23):1716-25. doi: 10.1056/NEJM200006083422306.
3
Neuropsychiatric problems in 2,500 long-term young travelers to the tropics.2500名前往热带地区的长期年轻旅行者的神经精神问题。
J Travel Med. 2000 Jan;7(1):5-9. doi: 10.2310/7060.2000.00002.
4
Malaria at Christmas: risks of prophylaxis versus risks of malaria.圣诞节期间的疟疾:预防的风险与疟疾的风险
BMJ. 1998 Nov 28;317(7171):1506-8. doi: 10.1136/bmj.317.7171.1506.
5
Mefloquine to prevent malaria: a systematic review of trials.甲氟喹预防疟疾:试验的系统评价
BMJ. 1997 Nov 29;315(7120):1412-6. doi: 10.1136/bmj.315.7120.1412.
6
Comparison of adverse events associated with use of mefloquine and combination of chloroquine and proguanil as antimalarial prophylaxis: postal and telephone survey of travellers.使用甲氟喹与氯喹和氯胍联合用药作为疟疾预防措施的不良事件比较:旅行者的邮寄和电话调查
BMJ. 1996 Aug 31;313(7056):525-8. doi: 10.1136/bmj.313.7056.525.
7
Mefloquine.甲氟喹
BMJ. 1994 Jan 29;308(6924):286-7. doi: 10.1136/bmj.308.6924.286.
8
Adverse reaction to mefloquine associated with ethanol ingestion.与摄入乙醇相关的甲氟喹不良反应。
CMAJ. 1995 Feb 15;152(4):515-7.
9
Acute psychosis after mefloquine.甲氟喹致急性精神病
Lancet. 1989 Jul 29;2(8657):282. doi: 10.1016/s0140-6736(89)90474-1.

Mefloquine: contraindicated in patients with mood, psychotic or seizure disorders.

作者信息

Wooltorton Eric

出版信息

CMAJ. 2002 Nov 12;167(10):1147.

PMID:12427708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC134297/
Abstract
摘要