Tokunaga Takanari, Ohno Shoji, Tajima Syunji, Oshikawa Katsuhisa, Hironaka Mitsugu, Sugiyama Yukihiko
Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, Tochigi, Japan.
Nihon Kokyuki Gakkai Zasshi. 2002 Aug;40(8):692-6.
The patient was a 56-year-old man who had received diagnoses of psoriasis vulgaris at the age of thirty-three and of nephrotic syndrome at forty-five, and had been treated with prednisolone. He consulted the outpatient clinic because of a cough, and interstitial pneumonia was diagnosed. He was admitted to our hospital because his symptoms and chest radiographic findings continued to worsen under treatment with antitussives. Chest radiography revealed a linear-reticular shadow in the lower lung fields. Chest computed tomography also revealed micro-cystic lesions, reticular shadows and traction bronchiectasis underneath the pleura at the back of both lower lobes. His serum titer of antinuclear antibody was increased, but he had no other symptoms or autoantibodies. Surgical lung biopsy under thoracoscopy revealed usual interstitial pneumonia (UIP). The association of interstitial pneumonia with psoriasis vulgaris is rare.
患者为一名56岁男性,33岁时被诊断为寻常型银屑病,45岁时被诊断为肾病综合征,曾接受泼尼松龙治疗。他因咳嗽到门诊就诊,被诊断为间质性肺炎。由于在使用止咳药治疗期间症状和胸部X线表现持续恶化,他被收治入院。胸部X线检查显示下肺野有线性网状阴影。胸部计算机断层扫描还显示两下叶后部胸膜下有微囊性病变、网状阴影和牵拉性支气管扩张。他的抗核抗体血清滴度升高,但没有其他症状或自身抗体。胸腔镜下手术肺活检显示为寻常型间质性肺炎(UIP)。寻常型银屑病与间质性肺炎的关联较为罕见。