O'Donnell Brian F, Potts Geoffrey F, Nestor Paul G, Stylianopoulos Kiriaki C, Shenton Martha E, McCarley Robert W
Department of Psychology, Indiana University, Bloomington 47405, USA.
J Abnorm Psychol. 2002 Nov;111(4):620-5. doi: 10.1037//0021-843x.111.4.620.
Pathways within the visual system can be distinguished on the basis of selectivity for low or high spatial frequencies. Spatial frequency discrimination was evaluated in 17 medicated male patients with schizophrenia and 19 male control subjects. Subjects were required to discriminate whether pairs of high contrast, sinusoidally modulated gratings were the same or different in spatial frequency. Accuracy performance was compared at high, medium, and low spatial frequencies on tasks matched for control performance. Patients showed a greater performance decrement of 12% on low as compared with 4% on high spatial frequencies. These findings suggest a disturbance of right hemisphere mechanisms involved in spatial perception and attention in schizophrenia.
视觉系统中的通路可以根据对低空间频率或高空间频率的选择性来区分。对17名正在服药的男性精神分裂症患者和19名男性对照受试者进行了空间频率辨别评估。受试者需要辨别高对比度、正弦调制光栅对在空间频率上是否相同。在与对照表现相匹配的任务中，比较了高、中、低空间频率下的准确性表现。与高空间频率下4%的表现下降相比，患者在低空间频率下的表现下降幅度更大，为12%。这些发现表明，精神分裂症患者右半球参与空间感知和注意力的机制受到了干扰。
