Cho S, Chang S E, Choi J H, Sung K J, Moon K C, Koh J K
Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Songpa-gu, Seoul, Korea.
J Eur Acad Dermatol Venereol. 2002 Sep;16(5):519-21. doi: 10.1046/j.1468-3083.2002.00499.x.
Plexiform fibrohistiocytic tumour is a low-grade malignant mesenchymal neoplasm of myofibroblastic origin with the capacity for biphasic differentiation toward a fibroblastic or histiocyte-like morphology. We report a case of this rare tumour presenting as a tender subcutaneous nodule on the scalp of a 58-year-old man. Histopathological examination revealed multinodular biphasic proliferation of fibroblast-like and histiocyte-like cells with a few osteoclast-like giant cells. This case is notable for the rare myxoid changes, which may reflect a different behaviour of this tumour when occurring in older people.
丛状纤维组织细胞瘤是一种起源于肌成纤维细胞的低级别恶性间叶性肿瘤，具有向成纤维细胞或组织细胞样形态双向分化的能力。我们报告了一例发生在一名58岁男性头皮上的表现为压痛性皮下结节的这种罕见肿瘤。组织病理学检查显示成纤维细胞样和组织细胞样细胞呈多结节性双向增生，并伴有一些破骨细胞样巨细胞。该病例因罕见的黏液样改变而值得关注，这可能反映了该肿瘤在老年人中发生时的不同行为。
