Farooq Afgan, Choudhary M Iqbal, Tahara Satoshi, Başer K Hüsnü Can, Demirci Fatih
International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Pakistan.
Z Naturforsch C J Biosci. 2002 Sep-Oct;57(9-10):863-6. doi: 10.1515/znc-2002-9-1018.
Detoxification of an antifungal monoterpene terpinolene (1) by the plant pathogenic fungus Botrytis cinerea afforded hydroxlyated metabolites 2,3-dihydro-3beta,6beta-dihydroxy-terpinolene (2) (39%) and 2,3-dihydro-1alpha,3alpha-dihydroxy-terpinolene (3) (20%), respectively. Terpinolene showed good levels of antifungal activity while both the metabolites were inactive against another plant pathogenic fungus Cladosporium herbarun.
