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1型糖尿病强化治疗:一项治疗性患者教育计划的一年期前瞻性评估。

Intensified treatment of type 1 diabetes: prospective evaluation at one year of a therapeutic patient education programme.

作者信息

Lemozy-Cadroy S, Crognier S, Gourdy P, Chauchard M C, Chale J P, Tauber Dagger J P, Hanaire-Broutin H

机构信息

Department of Diabetology, Rangueil University Hospital, Toulouse, France.

出版信息

Diabetes Metab. 2002 Sep;28(4 Pt 1):287-94.

Abstract

BACKGROUND

Type 1 diabetes treatment requires not only an intensive insulin regimen, but also intensive management, which daily involves participation of the patient. Our aim was to prospectively evaluate the efficacy on patient skills and metabolic control of our routine 5-day in-patient education programme.

METHODS

Over one year, each type 1 diabetic patient undertaking the programme for the first time, and able to complete a 2, 6, and 12 month follow-up, participated in the study (n=76). At baseline (T0), 61 patients had intensified insulin treatment and 15 increased from 2 to 3 daily insulin injections during the hospital stay. Using questionnaires and analysis of a glycaemia logbook, we evaluated at T0, T2, T6 and T12 patient skills related to diet, physical exercise, self-monitoring of blood glucose (SMBG), adjustment of insulin doses, and treatment of hypoglycaemia. Metabolic control was evaluated at the same time.

RESULTS

At one year, the following skills improved: Intake of carbohydrates (T0: 59%, T12: 90% of patients, p<0.001) and snacks (p<0.001), appropriate physical exercise (p<0.001), frequency of SMBG (T0: 3.3 +/- 1.5/day, T12: 4.5 +/- 1/day, p<0.001), frequency of post-prandial tests (p<0.001) and adjustment of insulin doses (T0: 18%, T12: 53% of patients, p<0.001). More patients always carried sugar (T0: 61%, T12: 97%, p<0.001) and appropriately treated hypoglycaemia (T0: 48%, T12: 79%, p<0.001). Concurrently, HbA(1c) decreased (T0: 8.6 +/- 1.5%, T12: 7.7 +/- 0.9%, p<0.001), and the frequency of hypoglycaemia was reduced (p<0.001). There was a correlation between the decrease of HbA(1c) and the frequency of SMBG (p<0.001, r2=0,24).

CONCLUSIONS

Education led to positive changes in patient skills, which were maintained over one year and were associated with improved metabolic control.

摘要

背景

1型糖尿病的治疗不仅需要强化胰岛素治疗方案,还需要强化管理,这需要患者每天参与。我们的目的是前瞻性评估我们常规的5天住院教育计划对患者技能和代谢控制的疗效。

方法

在一年多的时间里,每一位首次参加该计划且能够完成2个月、6个月和12个月随访的1型糖尿病患者参与了研究(n = 76)。在基线时(T0),61例患者进行了强化胰岛素治疗,15例患者在住院期间将每日胰岛素注射次数从2次增加到3次。通过问卷调查和分析血糖日志,我们在T0、T2、T6和T12评估了患者在饮食、体育锻炼、自我血糖监测(SMBG)、胰岛素剂量调整和低血糖治疗方面的技能。同时评估代谢控制情况。

结果

一年时,以下技能得到改善:碳水化合物摄入量(T0:59%,T12:90%的患者,p<0.001)和零食摄入量(p<0.001)、适当的体育锻炼(p<0.001)、SMBG频率(T0:3.3±1.5次/天,T12:4.5±1次/天,p<0.001)、餐后检测频率(p<0.001)以及胰岛素剂量调整(T0:18%,T12:53%的患者,p<0.001)。更多患者总是携带糖(T0:61%,T12:97%,p<0.001)并能适当治疗低血糖(T0:48%,T12:79%,p<0.001)。同时,糖化血红蛋白(HbA1c)下降(T0:8.6±1.5%,T12:7.7±0.9%,p<0.001),低血糖频率降低(p<0.001)。HbA1c的下降与SMBG频率之间存在相关性(p<0.001,r2 = 0.24)。

结论

教育使患者技能产生了积极变化,这些变化在一年中得以维持,并与改善的代谢控制相关。

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