Shao Zhi-Yu, Zhu Da-Yuan, Guo Yue-Wei
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People's Republic of China.
J Nat Prod. 2002 Nov;65(11):1675-7. doi: 10.1021/np020087x.
Three new polyoxygenated steroids, nanjiol A (1), B (2), and C (3), were isolated from an East China Sea soft coral Nephthea bayeri, and their structures were characterized by spectroscopic methods and comparison with known compounds. The new molecules were structurally related to (20S)-cholesta-1,4-diene-18,20-diol-3-one (4), a typical metabolite from the black coral Antipathes subpinnata.
从中国东海软珊瑚巴氏软珊瑚(Nephthea bayeri)中分离出三种新的多氧甾体化合物,南焦醇A(1)、B(2)和C(3),并通过光谱方法以及与已知化合物对比对其结构进行了表征。这些新分子在结构上与(20S)-胆甾-1,4-二烯-18,20-二醇-3-酮(4)相关,(4)是黑珊瑚亚羽状反口珊瑚(Antipathes subpinnata)的一种典型代谢产物。