Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan.
Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Mar Drugs. 2012 Jun;10(6):1288-1296. doi: 10.3390/md10061288. Epub 2012 Jun 6.
In order to search for novel bioactive substances from marine organisms, we investigated the acetone extract of the soft coral Nephthea chabrolii collected at San-Hsian-Tai, Taitong County, Taiwan. From this extract three new 19-oxygenated steroids, nebrosteroids N-P (1-3) were isolated. The structures of these compounds were elucidated by extensive spectroscopic analyses.
为了从海洋生物中寻找新型生物活性物质,我们研究了采自台湾大统县三仙台的软珊瑚 Nephthea chabrolii 的丙酮提取物。从该提取物中分离得到了三种新型 19-氧代甾体化合物,即 nebros teroids N-P(1-3)。通过广泛的光谱分析阐明了这些化合物的结构。