El Amrani Mohammed, Ducros Anne, Boulan Pauline, Aidi Saadia, Crassard Isabelle, Visy Jean Marc, Tournier-Lasserve Elisabeth, Bousser Marie Germaine
Service de Neurologie, Clinique de Courlancy, Reims, France.
Headache. 2002 Nov-Dec;42(10):974-7. doi: 10.1046/j.1526-4610.2002.02226.x.
To investigate the familial occurrence of cluster headache in a series of French patients fulfilling the International Headache Society diagnosis criteria.
One hundred eighty-six index patients and 624 first-degree relatives were surveyed.
A positive family history of cluster headache was found in 20 index patients (10.75%) with 22 affected first-degree relatives (3.4%). In multiplex families 6 of the 68 second-degree relatives that were contacted had cluster headache.
No precise mode of inheritance could be drawn from the observed repartition of cases within multiplex families.
在一系列符合国际头痛协会诊断标准的法国患者中调查丛集性头痛的家族发病情况。
对186例索引患者和624名一级亲属进行了调查。
在20例索引患者（10.75%）中发现有丛集性头痛的阳性家族史，有22名受影响的一级亲属（3.4%）。在多个家族中，所联系的68名二级亲属中有6人患有丛集性头痛。
从多个家族中观察到的病例分布情况无法得出确切的遗传模式。
