Boonen Annelies, Dagnelie Pieter C, Feleus Anita, Hesselink Martine A, Muris Jean W, Stockbrügger Reinhold W, Russel Maurice G
Department of Rheumatology, University Hospital Maastricht, University Maastricht, The Netherlands.
Inflamm Bowel Dis. 2002 Nov;8(6):382-9. doi: 10.1097/00054725-200211000-00002.
Inflammatory bowel diseases are chronic conditions that might cause a severe impact on social life. The aim of the study was to assess employment, chronic work disability, and sick leave in patients with inflammatory bowel disease.
A postal questionnaire was sent to 984 patients with inflammatory bowel disease and 1504 controls. Age- and gender-adjusted employment and chronic work disability ratios and rates were calculated using indirect standardization. In subjects in paid employment, proportions of those having an episode of sick leave and lost workdays were analyzed. Logistic regression was used to assess the contribution of age, gender, education, and course of disease.
The results of 680 (69%) patients and 715 (48%) controls could be analyzed. For the entire group of patients, employment was 6.5% lower, compared with controls (95% CI: 4.0-9.0). Chronic work disability was 17.1% higher than expected (95% CI: 15.1-19.1). In those in paid employment, 62% of patients compared with 53% of controls had experienced one or more episodes of sick leave during the past year (p = 0.002). This resulted in 19.2 versus 11.8 days of sick leave per subject per year for patients and controls respectively (p = 0.002). Relative to controls, the risk of chronic work disability was more increased in younger (p = 0.02) and higher educated (p = 0.02) patients. Course of disease contributed to chronic work disability and sick leave.
IBD has a significant impact on labor force participation that is higher in CD compared with UC and highest in younger and more highly educated patients.
炎症性肠病是慢性疾病,可能对社会生活造成严重影响。本研究的目的是评估炎症性肠病患者的就业情况、慢性工作残疾和病假情况。
向984例炎症性肠病患者和1504例对照者发送了邮政调查问卷。使用间接标准化方法计算年龄和性别调整后的就业和慢性工作残疾比率及发生率。在有薪就业的受试者中,分析了有病假经历和工作日损失的比例。使用逻辑回归评估年龄、性别、教育程度和疾病病程的影响。
可以分析680例(69%)患者和715例(48%)对照者的结果。与对照者相比,整个患者组的就业率低6.5%(95%CI:4.0 - 9.0)。慢性工作残疾比预期高17.1%(95%CI:15.1 - 19.1)。在有薪就业者中,过去一年中有62%的患者与53%的对照者经历过一次或多次病假(p = 0.002)。这导致患者和对照者每年每人的病假天数分别为19.2天和11.8天(p = 0.002)。相对于对照者,年轻患者(p = 0.02)和受过高等教育的患者(p = 0.02)慢性工作残疾的风险增加更多。疾病病程导致慢性工作残疾和病假。
炎症性肠病对劳动力参与有重大影响,克罗恩病的影响高于溃疡性结肠炎,在年轻和受过高等教育的患者中影响最大。