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用三氯乙酸对痤疮瘢痕进行局部治疗:皮肤瘢痕化学重建法

Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method.

作者信息

Lee Jung Bock, Chung Woo Gil, Kwahck Ho, Lee Kwang Hoon

机构信息

Leejiham Skin Clinic and Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Dermatol Surg. 2002 Nov;28(11):1017-21; discussion 1021. doi: 10.1046/j.1524-4725.2002.02095.x.

DOI:10.1046/j.1524-4725.2002.02095.x
PMID:12460296
Abstract

BACKGROUND

Acne scarring is a common complication of acne and yet no appropriate and effective single treatment modality has been developed. We suggest a technique consisting of the focal application of higher trichloroacetic acid (TCA) concentrations by pressing hard on the entire depressed area of atrophic acne scars. This technique is called chemical reconstruction of skin scars (CROSS) by the authors.

OBJECTIVE

To evaluate the clinical effects of CROSS on atrophic acne scars in dark-complexioned patients.

METHODS

An analysis was conducted of 65 patients with atrophic acne scars who were treated with CROSS in our hospitals between July 1996 and July 2001. Thirty-three patients were treated with 65% TCA CROSS and 32 patients were treated with 100% TCA CROSS. All patients had Fitzpatrick skin types IV-V.

RESULTS

Patient treatment data indicated that 27 of 33 patients (82%) (the 65% TCA group) and 30 of 32 patients (94%) (the 100% TCA group) experienced a good clinical response. All patients in the 100% TCA group who received five or six courses of treatment showed excellent results. Good satisfaction rates in the 65% and 100% TCA groups were recorded. There were no cases of significant complication.

CONCLUSION

CROSS is a safe and very effective single modality for the treatment of atrophic acne scars with no significant complications.

摘要

背景

痤疮瘢痕是痤疮常见的并发症,但尚未开发出合适且有效的单一治疗方式。我们提出一种技术,即通过用力按压萎缩性痤疮瘢痕的整个凹陷区域,局部应用高浓度三氯乙酸(TCA)。作者将此技术称为皮肤瘢痕化学重建(CROSS)。

目的

评估CROSS对深肤色患者萎缩性痤疮瘢痕的临床效果。

方法

对1996年7月至2001年7月间在我院接受CROSS治疗的65例萎缩性痤疮瘢痕患者进行分析。33例患者接受65% TCA CROSS治疗,32例患者接受100% TCA CROSS治疗。所有患者的皮肤类型均为Fitzpatrick IV - V型。

结果

患者治疗数据表明,33例患者中的27例(82%)(65% TCA组)和32例患者中的30例(94%)(100% TCA组)获得了良好的临床反应。100% TCA组中所有接受五或六个疗程治疗的患者均显示出极佳效果。65%和100% TCA组的满意度较高。未出现严重并发症病例。

结论

CROSS是一种安全且非常有效的单一治疗萎缩性痤疮瘢痕的方式,无明显并发症。

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