人工核糖核酸酶：在GpX和PypA磷酸二酯键处切割RNA的寡核苷酸-肽缀合物。 - Suppr

Artificial ribonucleases: oligonucleotide-peptide conjugates that cleave RNA at the GpX and PypA phosphodiester bonds.

作者信息

Mironova N L, Pyshnyi D V, Ivanova E M, Zenkova M A, Gross G J, Vlasov V V

机构信息

Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, pr. Akademika Lavrent'eva 8, Novosibirsk, 630090 Russia.

出版信息

Dokl Biochem Biophys. 2002 Jul-Aug;385:196-200. doi: 10.1023/a:1019907305751.

DOI:10.1023/a:1019907305751

PMID:12462971

Abstract

摘要

相似文献

Artificial ribonucleases: oligonucleotide-peptide conjugates that cleave RNA at the GpX and PypA phosphodiester bonds.人工核糖核酸酶：在GpX和PypA磷酸二酯键处切割RNA的寡核苷酸-肽缀合物。

Dokl Biochem Biophys. 2002 Jul-Aug;385:196-200. doi: 10.1023/a:1019907305751.

G-specific RNA-cleaving conjugates of short peptides and oligodeoxyribonucleotides.短肽与寡脱氧核糖核苷酸的G特异性RNA切割偶联物。

J Biomol Struct Dyn. 2006 Jun;23(6):591-602. doi: 10.1080/07391102.2006.10507084.

[Artificial ribonucleases I. Targeted RNA cleavage by 5'-peptidyloligodeoxyribonucleotides containing arginine and leucine residues].[人工核糖核酸酶I. 含精氨酸和亮氨酸残基的5'-肽基寡脱氧核糖核苷酸对RNA的靶向切割]

Bioorg Khim. 1997 Jun;23(6):497-504.

Design and synthesis of metal-free artificial ribonucleases.无金属人工核糖核酸酶的设计与合成。

Protein Pept Lett. 2007;14(2):151-63. doi: 10.2174/092986607779816177.

Covalently attached oligodeoxyribonucleotides induce RNase activity of a short peptide and modulate its base specificity.共价连接的寡脱氧核糖核苷酸可诱导一种短肽的核糖核酸酶活性并调节其碱基特异性。

Nucleic Acids Res. 2004 Mar 26;32(6):1928-36. doi: 10.1093/nar/gkh514. Print 2004.

Properties of nicked and circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligodeoxynucleotides.含有反义磷酸二酯寡脱氧核苷酸的带切口和环状哑铃状RNA/DNA嵌合寡核苷酸的特性

Bioorg Med Chem. 1998 Jul;6(7):1025-32. doi: 10.1016/s0968-0896(98)00060-1.

Oligonucleotide based artificial nuclease (OBAN) systems. Bulge size dependence and positioning of catalytic group in cleavage of RNA-bulges.基于寡核苷酸的人工核酸酶（OBAN）系统。RNA凸起切割中凸起大小依赖性及催化基团的定位。

Org Biomol Chem. 2003 May 7;1(9):1461-5. doi: 10.1039/b212216b.

Determination of the nucleotide conformation in the productive enzyme-substrate complexes of RNA-depolymerases.

FEBS Lett. 1997 Mar 10;404(2-3):169-72. doi: 10.1016/s0014-5793(97)00092-6.

Design and synthesis of peptide-oligonucleotide conjugates as potential artificial ribonucleases.

Nucleic Acids Symp Ser (Oxf). 2008(52):529-30. doi: 10.1093/nass/nrn268.

Synthesis of small multifunctional molecules having nucleic acid binding property.

Nucleic Acids Res Suppl. 2001(1):69-70. doi: 10.1093/nass/1.1.69.

引用本文的文献

Site-Selective Artificial Ribonucleases: Renaissance of Oligonucleotide Conjugates for Irreversible Cleavage of RNA Sequences.位点选择性人工核糖核酸酶：用于RNA序列不可逆切割的寡核苷酸缀合物的复兴

Molecules. 2021 Mar 19;26(6):1732. doi: 10.3390/molecules26061732.

RNase T1 mimicking artificial ribonuclease.核糖核酸酶T1模拟人工核糖核酸酶

Nucleic Acids Res. 2007;35(7):2356-67. doi: 10.1093/nar/gkm143. Epub 2007 Mar 27.

Nucleic Acids Res. 2004 Mar 26;32(6):1928-36. doi: 10.1093/nar/gkh514. Print 2004.

本文引用的文献

Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs.核糖核酸酶和核酶的无机模拟物：从随机切割到序列特异性化学再到催化性反义药物

Chem Rev. 1998 May 7;98(3):939-960. doi: 10.1021/cr960422k.

RNA cleavage by 1,4-diazabicyclo[2.2.2]octane-imidazole conjugates.

Methods Enzymol. 2001;341:468-90. doi: 10.1016/s0076-6879(01)41171-2.

[Site-specific cleavage of yeast tRNA(Phe) by derivatives of oligonucleotides bearing bisimidazole groups].

Dokl Akad Nauk. 1999 Dec;369(6):827-30.

Enhancement of RNA self-cleavage by micellar catalysis.通过胶束催化增强RNA自我切割

FEBS Lett. 1999 Aug 27;457(2):193-9. doi: 10.1016/s0014-5793(99)01038-8.

Highly efficient endonucleolytic cleavage of RNA by a Cys(2)His(2) zinc-finger peptide.一种Cys(2)His(2)锌指肽对RNA进行高效核酸内切酶切割

Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10010-5. doi: 10.1073/pnas.96.18.10010.

[Chemical ribonucleases].

Mol Biol (Mosk). 1998 Jan-Feb;32(1):62-70.

Site-specific cleavage of tRNA by imidazole and/or primary amine groups bound at the 5'-end of oligodeoxyribonucleotides.通过与寡脱氧核糖核苷酸5'端结合的咪唑和/或伯胺基团对tRNA进行位点特异性切割。

Biochim Biophys Acta. 1998 Feb 2;1379(2):217-23. doi: 10.1016/s0304-4165(97)00101-3.

[Mg2+ ions differently affect the physical properties of tRNA(Phe) and the transcript of its gene].镁离子对苯丙氨酸转运核糖核酸（tRNA(Phe)）及其基因转录本的物理性质有不同影响。

Mol Biol (Mosk). 1997 Sep-Oct;31(5):894-900.

Bioorg Khim. 1997 Jun;23(6):497-504.

[RNA hydrolysis catalyzed by imidazole as a reaction for studying the secondary structure of RNA and complexes of RNA with oligonucleotides].[咪唑催化的RNA水解反应用于研究RNA的二级结构以及RNA与寡核苷酸的复合物]

Dokl Akad Nauk. 1996 Jul;349(3):411-3.

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Artificial ribonucleases: oligonucleotide-peptide conjugates that cleave RNA at the GpX and PypA phosphodiester bonds.

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