Yachnis Anthony T
Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine and Brain Institute, Gainesville, FL, USA.
Semin Diagn Pathol. 2002 Nov;19(4):192-206.
The pathologist responsible for nervous system intraoperative consultations must know basics of the clinical history, details of the location and imaging characteristics of the lesion, and must be familiar with known clinicopathologic entities. Although cytologic and frozen section techniques have not changed significantly in the past 15 years, significant advancements in neuroimaging have greatly improved the ability to generate an accurate preoperative differential diagnosis. Such information can greatly aid the pathologist during intraoperative consultation. This review concerns the intraoperative cytologic and frozen section findings of the major clinicopathologic entities encountered in surgical neuropathology. While neoplastic processes of the central nervous system will be emphasized, important non-neoplastic conditions that mimic brain tumors will also be covered. A basic clinicopathologic approach to successful neurosurgical intra-operative consultation is provided.
负责神经系统术中会诊的病理学家必须了解临床病史的基本情况、病变部位的细节和影像学特征，并且必须熟悉已知的临床病理实体。尽管在过去15年中细胞学和冰冻切片技术没有显著变化，但神经影像学的重大进展极大地提高了术前准确鉴别诊断的能力。这些信息在术中会诊时能极大地帮助病理学家。本综述涉及手术神经病理学中遇到的主要临床病理实体的术中细胞学和冰冻切片检查结果。虽然将重点关注中枢神经系统的肿瘤性病变，但也将涵盖模仿脑肿瘤的重要非肿瘤性疾病。本文提供了一种成功进行神经外科术中会诊的基本临床病理方法。
