Yanagisawa Shuichi
Dept of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro, Tokyo, Japan.
Trends Plant Sci. 2002 Dec;7(12):555-60. doi: 10.1016/s1360-1385(02)02362-2.
Dof proteins are members of a major family of plant transcription factors. The proteins have similar DNA-binding properties because of the highly conserved DNA-binding domain. However, recent studies are disclosing their diverse roles in gene expression when associated with plant-specific phenomena including light, phytohormone and defense responses, seed development and germination. Based on the structural diversity indicated by the complete catalog of Arabidopsis Dof proteins, Dof genes appear to have evolved multiple times, preceding and paralleling the diversification of angiosperms. Such gene multiplication might have led to the functional diversification of Dof proteins proceeding differently in distinct plant species.
Dof蛋白是植物转录因子主要家族的成员。由于高度保守的DNA结合结构域，这些蛋白具有相似的DNA结合特性。然而，最近的研究揭示了它们在与包括光、植物激素和防御反应、种子发育和萌发等植物特异性现象相关的基因表达中具有多种作用。基于拟南芥Dof蛋白完整目录所显示的结构多样性，Dof基因似乎已经多次进化，先于被子植物的多样化并与之平行。这种基因倍增可能导致了Dof蛋白在不同植物物种中以不同方式进行功能多样化。
