Kohner E M, Hamilton A M, Joplin G F, Fraser T R
Diabetes. 1976 Feb;25(2):104-10. doi: 10.2337/diab.25.2.104.
A group of 34 patients with florid diabetic retinopathy are reported. Nine of these had at least one eye untreated and of these only two maintained vision at one year-the others were blind. Ten patients had 11 florid eyes treated by photocoagulation. At one year six were blind and five had good vision. At two years only three could still see. Of 20 pituitary-ablated patients with 29 florid eyes, only three were blind at one year. Even at five years, 12 of 17 eyes could see and only two patients were blind. The one- and two-year visual acuities were significantly better in the pituitary ablated eyes than in the untreated and photocoagulated ones (p = 0.01-0.03). It is suggested that for this rare form of retinopathy pituitary ablation remains the treatment of choice if vision is to be maintained.
报告了一组34例患有增殖性糖尿病视网膜病变的患者。其中9例患者至少有一只眼睛未接受治疗,而在这些患者中,只有2例在一年后仍保持视力,其他患者均失明。10例患者的11只增殖性眼睛接受了光凝治疗。一年后,6例失明,5例视力良好。两年后,只有3例仍能看见。在20例接受垂体切除的患者中,有29只增殖性眼睛,一年后只有3例失明。即使在五年后,17只眼睛中有12只仍能看见,只有2例患者失明。垂体切除的眼睛在一年和两年时的视力明显优于未治疗和接受光凝治疗的眼睛(p = 0.01 - 0.03)。建议对于这种罕见的视网膜病变形式,如果要维持视力,垂体切除仍然是首选治疗方法。