Andersen Ross E, Franckowiak Shawn C, Bartlett Susan J, Fontaine Kevin R
Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
Metabolism. 2002 Dec;51(12):1528-33. doi: 10.1053/meta.2002.36304.
Moderate intensity physical activity achieved through changes in lifestyle may promote weight management. However, little is known about changes in physiologic and metabolic variables when patients lose weight using moderate intensity lifestyle activity instead of traditional structured vigorous aerobic exercise. To compare changes in resting metabolic energy expenditure (REE), fat mass (FM), and fat-free mass (FFM) associated with a 12-week weight loss program combined with either: (1) aerobic exercise (AER); or (2) lifestyle activity (LIFE), we randomized 39 overweight adults (mean body mass index [BMI] = 30.9 +/- 2.8 kg/m(2)) to either diet plus AER (N = 18) or diet plus LIFE (N = 21). Both groups consumed a self-selected diet of 1,200 to 1,800 kcal/d (5,021 to 7,531 kJ/d). The AER group performed vigorous aerobic exercise for up to 45 minutes 3 to 4 d/wk. The LIFE group accumulated 30 minutes of moderate intensity physical activity on most days of the week. Compliance with the respective protocols was monitored on a weekly basis. REE was measured before and after treatment via open-circuit spirometry. The AER group decreased body weight by 8.4% (P<.001)while the LIFE had a reduction of 6.7% (P <.001) after treatment. Over the course of the interventions, the AER and LIFE groups experienced 10.9% (P <.001) and 10.2% (P <.001) reductions in REE, respectively. Aerobic exercise did not prevent reductions in REE to a greater extent than did lifestyle activity in patients consuming a reduced calorie diet. Change in REE was not related to changes in FFM or FM for either group, and there were no differences between groups in reductions of REE, weight, FM, or FFM. A program of diet plus lifestyle physical activity may be a suitable alternative for dieting adults who have difficulty adhering to a program of vigorous activity.
通过改变生活方式实现的中等强度身体活动可能有助于体重管理。然而，对于患者采用中等强度生活方式活动而非传统的有组织的剧烈有氧运动来减肥时生理和代谢变量的变化，我们却知之甚少。为了比较与一项为期12周的减肥计划相关的静息代谢能量消耗（REE）、脂肪量（FM）和去脂体重（FFM）的变化，该计划结合了以下两种方式之一：（1）有氧运动（AER）；或（2）生活方式活动（LIFE），我们将39名超重成年人（平均体重指数[BMI]=30.9±2.8kg/m²）随机分为饮食加AER组（N = 18）或饮食加LIFE组（N = 21）。两组均采用自行选择的1200至1800千卡/天（5021至7531千焦/天）的饮食。AER组每周进行3至4天、每次长达45分钟的剧烈有氧运动。LIFE组在一周的大多数日子里积累30分钟的中等强度身体活动。每周监测对各自方案的依从性。通过开路肺活量测定法在治疗前后测量REE。治疗后，AER组体重下降了8.4%（P<.001），而LIFE组下降了6.7%（P<.001）。在干预过程中，AER组和LIFE组的REE分别下降了10.9%（P<.001）和10.2%（P<.001）。在摄入低热量饮食的患者中，有氧运动在防止REE下降方面并不比生活方式活动更有效。两组中REE的变化均与FFM或FM的变化无关，且两组在REE、体重、FM或FFM的下降方面没有差异。对于难以坚持剧烈活动计划的节食成年人来说，饮食加生活方式身体活动计划可能是一种合适的替代方案。
