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雌性小鼠的膳食蛋白质、寿命和生理变量。

Dietary protein life-span, and physiological variables in female mice.

作者信息

Leto S, Kokkonen G C, Barrows C H

出版信息

J Gerontol. 1976 Mar;31(2):149-54. doi: 10.1093/geronj/31.2.149.

DOI:10.1093/geronj/31.2.149
PMID:1249403
Abstract

The 50% mortality of female C57BL/6J mice fed ad libitum a diet which contained 26% or 4% casein, was 23.5 and 28 mo., respectively. Significantly lower rectal temperatures and higher oxygen consumptions were observed in the animals offered the 4% compared to the 26% casein diet. Changes in body temperature and oxygen consumption could not account for the total increase in life-span brought about by feeding a low protein diet.

摘要

随意喂食含26%或4%酪蛋白饮食的雌性C57BL/6J小鼠,其50%死亡率分别为23.5个月和28个月。与喂食含26%酪蛋白饮食的动物相比,喂食4%酪蛋白饮食的动物直肠温度显著更低,耗氧量更高。体温和耗氧量的变化并不能解释低蛋白饮食带来的寿命总体延长。

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