Labib M
Department of Clinical Biochemistry, Russells Hall Hospital, Dudley, West Midlands DY1 2HQ, UK.
J Clin Pathol. 2003 Jan;56(1):17-25. doi: 10.1136/jcp.56.1.17.
Obesity is a chronic condition characterised by an excess of body fat. It is a complex disorder of appetite regulation and energy metabolism controlled by specific biological factors. In the past 10 years, great progress has been made in the scientific understanding of the pathophysiology of obesity and the interactions between genetic predisposition to weight gain and the environment. This article will review the current understanding of the pathophysiology and the approach to the investigation and management of obesity.
肥胖是一种以体内脂肪过多为特征的慢性疾病。它是一种由特定生物因素控制的食欲调节和能量代谢的复杂紊乱。在过去十年中，在对肥胖病理生理学以及体重增加的遗传易感性与环境之间相互作用的科学认识方面取得了巨大进展。本文将综述目前对肥胖病理生理学的认识以及肥胖的调查和管理方法。
