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磁共振胰胆管造影在预测胆结石病患者胆总管结石中的价值。

The value of magnetic resonance cholangiopancreatography in predicting common bile duct stones in patients with gallstone disease.

作者信息

Topal B, Van de Moortel M, Fieuws S, Vanbeckevoort D, Van Steenbergen W, Aerts R, Penninckx F

机构信息

Department of Abdominal Surgery, University Hospital Gasthuisberg, Catholic University Leuven, Herestraat 49, 3000 Leuven, Belgium.

出版信息

Br J Surg. 2003 Jan;90(1):42-7. doi: 10.1002/bjs.4025.

Abstract

BACKGROUND

The application of available predictive scoring systems for the detection of common bile duct (CBD) stones has not reduced the number of patients who undergo unnecessary endoscopic retrograde cholangiopancreatography. The aim of this study was to create a predictive model for CBD stones and to assess the value of magnetic resonance cholangiopancreatography (MRCP) in prediction.

METHODS

In 1998, 366 patients with gallstone disease (118 males, 248 females; mean age 57 (range 8-84) years) underwent cholecystectomy. Statistical analysis was performed on patient data obtained at the time of first presentation.

RESULTS

CBD stones were demonstrated in 43 (12 per cent) of 366 patients. The predictive model for common duct stones included ultrasonography showing CBD stones or bile duct dilatation, age greater than 60 years, fever, serum alkaline phosphatase level above 670 units/l and serum amylase level above 95 units/l. In patients with a predicted probability greater than 5 per cent, CBD stones were present in 11 per cent, compared with 1 per cent in patients with a probability of 5 per cent or less. MRCP had an observed sensitivity of 95 per cent, specificity of 100 per cent, positive predictive value of 100 per cent and negative predictive value of 98 per cent.

CONCLUSION

In patients with a predicted probability for CBD stones of more than 5 per cent, MRCP is recommended in order to confirm the presence or absence of stones and as guidance in further management.

摘要

背景

现有的用于检测胆总管结石的预测评分系统的应用并未减少接受不必要的内镜逆行胰胆管造影术的患者数量。本研究的目的是创建一个胆总管结石预测模型,并评估磁共振胰胆管造影(MRCP)在预测中的价值。

方法

1998年,366例胆石症患者(男118例,女248例;平均年龄57岁(8 - 84岁))接受了胆囊切除术。对首次就诊时获得的患者数据进行了统计分析。

结果

366例患者中有43例(12%)发现胆总管结石。胆总管结石的预测模型包括超声显示胆总管结石或胆管扩张、年龄大于60岁、发热、血清碱性磷酸酶水平高于670单位/升和血清淀粉酶水平高于95单位/升。预测概率大于5%的患者中,胆总管结石的发生率为11%,而概率为5%或更低的患者中这一比例为1%。MRCP的观察到的敏感性为95%,特异性为100%,阳性预测值为100%,阴性预测值为98%。

结论

对于预测胆总管结石概率大于5%的患者,建议进行MRCP以确认结石的存在与否,并作为进一步治疗的指导。

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