Dahl Kristin H, Røkenes Torunn P, Lundblad Eirik W, Sundsfjord Arnfinn
Department of Microbiology and Virology, University and University Hospital of Tromsø Norwegian Institute of Gene Ecology, Tromsø, Norway.
Antimicrob Agents Chemother. 2003 Feb;47(2):786-9. doi: 10.1128/AAC.47.2.786-789.2003.
The vanB2 operon encoding glycopeptide resistance is an integral part of the putative conjugative transposon Tn5382. Characterization of clinical glycopeptide resistant derivatives from an epidemic ampicillin-resistant Enterococcus faecium strain showed precise chromosomal or plasmid insertions of a vanB2-containing Tn5382-like element. Conjugative transposition of the Tn5382-like element was not demonstrated in retransfer studies.
编码糖肽抗性的vanB2操纵子是推定的接合转座子Tn5382的一个组成部分。对一株流行的耐氨苄西林屎肠球菌临床糖肽抗性衍生物的特性分析表明,含vanB2的Tn5382样元件精确插入染色体或质粒。在再次转移研究中未证实Tn5382样元件的接合转座。