Mondal A, Kundu R, Misra D K
Department of Pathology, SVS Marwari Hospital and Cancer Detection Centre, Calcutta.
Indian J Pathol Microbiol. 2001 Jan;44(1):31-5.
Benign giant cell tumour of bone with metastases to other bones and lungs is extremely rare. Benign metastasising giant cell tumour is distinctly separate from multicentric giant cell tumour, primary and secondary malignant giant cell tumour. Factors regulating the local recurrence and metastatic potential of this benign tumour depend on its aggressiveness which can be better assessed by clinical and radiological parameters rather than the histopathological appearance. A benign giant cell tumour of ischium with metastasis to vertebra and lung over an eleven year period is discussed. Extreme paucity of literature prompted to publish the article. A short review of factors determining the recurrence and metastatic spread of benign giant cell tumour of bone is highlighted.
骨良性巨细胞瘤转移至其他骨骼和肺部极为罕见。良性转移性巨细胞瘤与多中心巨细胞瘤、原发性和继发性恶性巨细胞瘤明显不同。调节这种良性肿瘤局部复发和转移潜能的因素取决于其侵袭性，通过临床和放射学参数而非组织病理学表现能更好地评估这种侵袭性。本文讨论了一例坐骨良性巨细胞瘤在11年期间转移至椎骨和肺部的病例。由于相关文献极为匮乏，故撰写此文发表。文中还着重对决定骨良性巨细胞瘤复发和转移扩散的因素进行了简要综述。
