Bahri I, Ben Yahia N, Boudawara T, Makni S, Fakhfakh B, Kechaou S, Keskes H, Jlidi R
Laboratoire d'Anatomie et de Cytologie Pathologiques, CHU Habib-Bourguiba, 3029 Sfax, Tunisia.
Rev Chir Orthop Reparatrice Appar Mot. 2003 Jun;89(4):361-6.
Giant-cell tumors are an infrequent clinical, radiological, and pathological entity observed in 5% of primary bone tumors. They generally occur at the epiphysis of long bones, particularly in the knee area but patellar localization seems very rare. Despite their perfectly benign histological aspect, giant-cell tumors may be aggressive, leading to local recurrence or even distant metastasis to the lung. We report a case of benign giant-cell tumor of the patella with lung metastasis observed in a 23-year-old woman. The aggressive radiological image was suggestive of chondrosarcoma. Histologically the differential diagnosis with chondroblastoma was difficult. The tumor and lung metastasis were treated by surgical resection. Four years later there has been no recurrence. We present the anatomic and clinical aspects of giant-cell tumor of the bone together with the diagnostic approach and the clinical course.
骨巨细胞瘤是一种不常见的临床、放射学和病理学实体，在原发性骨肿瘤中占5%。它们通常发生在长骨的骨骺处，尤其是在膝关节区域，但髌骨部位的定位似乎非常罕见。尽管骨巨细胞瘤在组织学上表现为完全良性，但仍可能具有侵袭性，导致局部复发甚至肺远处转移。我们报告一例23岁女性髌骨良性骨巨细胞瘤伴肺转移的病例。其侵袭性的放射学影像提示为软骨肉瘤。在组织学上，与软骨母细胞瘤进行鉴别诊断很困难。肿瘤及肺转移灶均通过手术切除进行治疗。四年后未出现复发。我们展示了骨巨细胞瘤的解剖学和临床特征，以及诊断方法和临床过程。
