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哮喘和慢性阻塞性肺疾病发病机制中的饮食因素

Dietary factors in the pathogenesis of asthma and chronic obstructive pulmonary disease.

作者信息

Denny Sarah I, Thompson Rachel L, Margetts Barrie M

机构信息

Public Health Nutrition, Institute of Human Nutrition, University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

出版信息

Curr Allergy Asthma Rep. 2003 Mar;3(2):130-6. doi: 10.1007/s11882-003-0025-6.

Abstract

This review focuses on the role of dietary factors in the pathogenesis of asthma and chronic obstructive pulmonary disease. Reduced pulmonary function and indicators of airway obstruction have been shown to be strong indicators of mortality; therefore, a link with diet in the pathogenesis of these diseases would have important public health implications. The results of the studies identified in the review suggest that people who have a diet rich in fruit and vegetables have a lower risk of poor respiratory health, and that this may be due to the antioxidant nutrients these foods contain. On the basis of the evidence, it seems justified to promote a healthy diet, high in fruits, vegetables, and whole grain foods and low in alcohol and fatty foods, as set out in existing guidelines for prevention of cardiovascular disease and cancer, to protect respiratory health in both children and adults.

摘要

本综述聚焦于饮食因素在哮喘和慢性阻塞性肺疾病发病机制中的作用。肺功能降低和气道阻塞指标已被证明是死亡率的有力指标;因此,这些疾病发病机制与饮食之间的联系具有重要的公共卫生意义。综述中所确定的研究结果表明,食用富含水果和蔬菜饮食的人群呼吸健康状况较差的风险较低,这可能是由于这些食物所含的抗氧化营养素。基于现有证据,推广一种健康饮食似乎是合理的,即如预防心血管疾病和癌症的现有指南中所规定的,多吃水果、蔬菜和全谷物食品,少饮酒和少吃高脂肪食物,以保护儿童和成人的呼吸健康。

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