Berthon Bronwyn S, Wood Lisa G
Centre for Asthma and Respiratory Diseases, Level 2, Hunter Medical Research Institute, University of Newcastle, Lot 1 Kookaburra Circuit, New Lambton Heights, NSW 2305, Australia.
Nutrients. 2015 Mar 5;7(3):1618-43. doi: 10.3390/nu7031618.
Diet and nutrition may be important modifiable risk factors for the development, progression and management of obstructive lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). This review examines the relationship between dietary patterns, nutrient intake and weight status in obstructive lung diseases, at different life stages, from in-utero influences through childhood and into adulthood. In vitro and animal studies suggest important roles for various nutrients, some of which are supported by epidemiological studies. However, few well-designed human intervention trials are available to definitively assess the efficacy of different approaches to nutritional management of respiratory diseases. Evidence for the impact of higher intakes of fruit and vegetables is amongst the strongest, yet other dietary nutrients and dietary patterns require evidence from human clinical studies before conclusions can be made about their effectiveness.
饮食和营养可能是哮喘和慢性阻塞性肺疾病(COPD)等阻塞性肺病发生、发展和管理的重要可改变风险因素。本综述探讨了在不同生命阶段,从子宫内影响到儿童期再到成年期,阻塞性肺病患者的饮食模式、营养摄入与体重状况之间的关系。体外和动物研究表明多种营养素发挥着重要作用,其中一些得到了流行病学研究的支持。然而,几乎没有经过精心设计的人体干预试验来明确评估不同营养管理方法对呼吸系统疾病的疗效。摄入更多水果和蔬菜的影响证据最为充分,但在得出其他膳食营养素和饮食模式有效性的结论之前,还需要人体临床研究的证据。