Gundelfinger Eckart D, Kessels Michael M, Qualmann Britta
Leibniz Institute for Neurobiology, Department of Neurochemistry and Molecular Biology, Brenneckestr. 6, 39118 Magdeburg, Germany.
Nat Rev Mol Cell Biol. 2003 Feb;4(2):127-39. doi: 10.1038/nrm1016.
In secretory cells, exocytosis and compensatory endocytosis are tightly coupled membrane trafficking processes that control the surface area and composition of the plasma membrane. While exocytic and endocytic processes have been studied independently in great detail, at present there is much interest in understanding the mode of their coupling. This review discusses emerging insights into the coupling of these processes, both in the chemical synapses of neurons and in non-neuronal cells.
在分泌细胞中，胞吐作用和补偿性内吞作用是紧密耦合的膜运输过程，它们控制着质膜的表面积和组成。虽然胞吐和内吞过程已分别得到了深入研究，但目前人们对了解它们的耦合方式很感兴趣。这篇综述讨论了在神经元的化学突触和非神经元细胞中这些过程耦合的新见解。
