Dubroff L M, Nemer M
Nature. 1976 Mar 11;260(5547):120-4. doi: 10.1038/260120a0.
Three molecular classes with different properties can be distinguished in the heterogeneous nuclear RNA (HnRNA) of sea urchin embryos. The relative proportions of these classes, which we have previously designated alpha, beta and gamma HnRNA, undergo marked changes during development from morula to early gastrula. Such changes suggest the existence of more than a single HnRNA function, as well as specific roles for different HnRNA classes in embryonic development.
在海胆胚胎的不均一核RNA(HnRNA)中,可以区分出具有不同特性的三类分子。我们之前将这些类别分别指定为α、β和γ HnRNA,从桑椹胚发育到早期原肠胚的过程中,这些类别的相对比例发生了显著变化。这种变化表明存在不止一种HnRNA功能,以及不同HnRNA类别在胚胎发育中的特定作用。